Magnesium and Riboflavin Treatment for Post-Concussion Headache

Magnesium and Riboflavin Treatment for Post-Concussion Headache

This clinical trial will try to determine if the supplements magnesium and riboflavin will reduce the pain and duration of headaches in persons diagnosed with a concussion. The participant will be randomized to either active magnesium and riboflavin capsules or placebo (inert) capsules. The capsules will be taken once a day for 14 days. The participant will also complete a short diary form for the 14 days and will have 3 follow up visits either by telephone or in person.

Inclusion Criteria:

• Seen at University of Virginia Student Health and Wellness Center or Emergency Department for Initial Visit for Concussion;
• Less than 3 days have elapsed since their injury;
• Able to swallow capsules

Exclusion Criteria:

• Concussion complicated by cranial bleed, skull fracture, additional severe injury;
• Kidney disfunction or failure;
• Significant gastro-intestinal dysfunction;
• Varsity Athlete;
• Two or more previous concussions;
• Women who are pregnant or breast feeding;
• Taking tetracycline, fluoroquinolone, iron digoxin, chlorpromazine or penicillamine