One of the limitations of organized cervical screening in the Czech Republic is the lack of participation in preventive gynecological examinations. The aim of the project is to evaluate the benefits of self-sampling for HPV DNA in general practitioners' outpatient clinics to improve population participation in cervical screening.

Organized cervical screening in the Czech Republic has a long-term participation rate of about 56% of the target population. Despite active invitations through health insurance companies, a part of the population is resistant and does not participate in screening visits to gynaecologists in the long term. A significant proportion of such women, however, regularly visit their general practitioner due to other comorbidities. The aim of the ASTRA project is to assess whether an effective way to increase the proportion of women attending cervical screening is to perform self-testing for HPV DNA in the GP's office.

Inclusion Criteria:

• Signed informed consent for statistical data processing and consent to the processing of personal data
• Age 30+
• HPV test never performed or performed more than 3 years ago or patient does not know

Exclusion Criteria:

• Refusal to participate
• Pregnancy and puerperium
• Menses
• History of hysterectomy
• HPV test performed <3 years ago with negative result
• Regular participation in screening and concurrent age 35, 45 or 55 years (test will be performed in the same year of screening).

All women over 30 years of age who meet the entry criteria for inclusion in the study.

All anonymised data will be available.