Prospective Feasibility Study of Endobronchial Ultrasound Transbronchial Cryobiopsy (EBUS-TBCB 1.1 mm Probe) Among Patients With Mediastinal Lymphadenopathies

Prospective Feasibility Study of Endobronchial Ultrasound Transbronchial Cryobiopsy (EBUS-TBCB 1.1 mm Probe) Among Patients With Mediastinal Lymphadenopathies

Mediastinal lymph nodes enlargement with short axis diameter >15 mm is conventionally defined as a mediastinal lymphadenopathy. The causes of mediastinal lymphadenopathy can be malignant or benign, (infectious, inflammatory, and other such as drug toxicity).

Inclusion Criteria:

• Patient ≥ 18 years of age
• Mediastinal and/or hilar lymphadenopathies > 20 mm on an injected chest CT scan
• Suspicion of lymphoproliferative disease, sarcoidosis or tuberculosis
• Hypermetabolism of mediastinal and/or hilar lymphadenopathies on PET scan (SUV max > 3)
• No contraindication for general anesthesia
• French-speaking Patient
• -Signed informed consent

Exclusion Criteria:

• Patient not covered by the French social security system
• Patient with legal protection
• Pregnant or breastfeeding patient (if applicable)
• Patient under guardianship or curatorship
• Patient deprived of liberty