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The main objective of this study is to investigate whether checklist-based close telephone consultation and process surveillance for S. aureus bacteraemia (SAB) can improve adherence to our in-house SAB-guidelines (prospective quality- improvement group).
In addition, the effects of telephone consultation on the clinical outcome of patients will be examined.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Retrospective control group (n= 62) | No Intervention | Analysis of patients with the diagnosis of S. aureus-bacteraemia between 01.10.2022-01.10.2023 | |
| Prospective quality-improvement group (n= 62) | Other | Analysis of patients with the diagnosis of S. aureus-bacteraemia between 22.01.2024-22.01.2025 |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Checklist-based phone calls | Other | The treating doctor will be called on day 1 and 12 after SAB diagnosis to point out the standard of care (as per our evidence-based in-hospital standard operating procedure (SOP)) for SAB. On day 2 and 6 after SAB diagnosis, there will be additional phone calls if clinical management does not follow hospital guidelines. The study team will also leave comments in the medical charts of the respective patients if the management does not follow hospital guidelines. |
| Measure | Description | Time Frame |
|---|---|---|
| SOP adherence, calculated as a sum score per patient with the following 8 parameters: |
| Hospital admission until hospital discharge (no later than day 90 after diagnosis) |
| Measure | Description | Time Frame |
|---|---|---|
| Time to specific antimicrobial treatment according to guidelines concerning agent and duration | Hospital admission until hospital discharge (no later than day 90 after diagnosis) | |
| Time to negativity of follow up blood cultures | Day of SAB diagnosis until hospital discharge (no later than day 90 after diagnosis) |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Greifswald University Medicine | Greifswald | Germany |
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| ID | Term |
|---|---|
| D013203 | Staphylococcal Infections |
| D016470 | Bacteremia |
| ID | Term |
|---|---|
| D016908 | Gram-Positive Bacterial Infections |
| D001424 | Bacterial Infections |
| D001423 | Bacterial Infections and Mycoses |
| D007239 | Infections |
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|
| Time till TEE is performed (when indicated) | Hospital admission until hospital discharge (no later than day 90 after diagnosis) |
| Length of hospital stay after SAB diagnosis | Day of SAB diagnosis until hospital discharge (no later than day 90 after diagnosis) |
| In-hospital mortality (all patients) | Hospital admission until hospital discharge (no later than day 90 after diagnosis) |
| In-hospital mortality (because of SAB complications) | Hospital admission until hospital discharge (no later than day 90 after diagnosis) |
| Hospital readmission until day 30 after SAB diagnosis (all patients) | Day of SAB diagnosis until day 30 after diagnosis |
| Hospital readmission until day 30 after SAB diagnosis (because of SAB complications) | Day of SAB diagnosis until day 30 after diagnosis |
| Hospital readmission until day 90 after SAB diagnosis (all patients) | Day of SAB diagnosis until day 90 after diagnosis |
| Hospital readmission until day 90 after SAB diagnosis (because of SAB complications) | Day of SAB diagnosis until day 90 after diagnosis |
| 90-day all-cause mortality | Day of SAB diagnosis until day 90 after diagnosis |
| 90-day mortality because of SAB complications | Day of SAB diagnosis until day 90 after diagnosis |
| Relapse of bacteremia until day 90 after diagnosis | Day of SAB diagnosis until day 90 after diagnosis |
| Quality of discharge summary (documentation and treatment plan), calculated as a sum score | Hospital admission until hospital discharge (no later than day 90 after diagnosis) |
| Infectious diseases consultation, when indicated (yes/no) | Hospital admission until hospital discharge (no later than day 90 after diagnosis) |
| D018805 | Sepsis |
| D018746 | Systemic Inflammatory Response Syndrome |
| D007249 | Inflammation |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |