The Role of Standardized Training in the Diagnosis of Interstitial Lung Disease by Transbronchial Lung Cryobiopsy

Learning Curve for the Diagnosis of Interstitial Lung Disease by Transbronchial Lung Cryobiopsy and the Role of Standardized Training in It

The aim of this study was to conduct a prospective randomized controlled trial to design simulator and in vitro lung standardized training, to perform a learning curve evaluation of transbronchial lung cryobiopsy (TBLC) operating physicians, and to assess the role of standardized training in TBLC.

Inclusion Criteria:

• Age ≥18 years
• suspected ILD.
• ≤3 months since HRCT
• Forced vital capacity (FVC) ≥50% of predicted value
• Diffused lung carbon monoxide (DLCO) ≥35% predicted value
• Echocardiography ≤ 12 months
• Estimated pulmonary artery systolic pressure ≤40 mmHg
• Body mass index (BMI) ≤35 kg/m2
• Patient consent for experimentation

Exclusion Criteria:

• Patients with platelet counts less than 50 × 109/L or prothrombin time international normalized ratio (INR) higher than 1.5
• Patients refused to participate in the experiment