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This research will overview the effect of aloe vera gel (AVG) as intra canal medicament in patients with asymptomatic periapical lesions. It will provide endodontists with scientific evidence regarding the beneficial use of AVG as an intracanal medicament owing to its superior antibacterial and analgesic properties as compared to routinely used commercial intra canal medicaments.
Objective: To evaluate the effect of aloe vera gel based on clinical signs and symptoms as an intracanal medicament in asymptomatic periapical lesions over a period of three weeks. Methodology: Fresh AVG will be prepared. It will be placed as intracanal medicament after cleaning and shaping in patients with asymptomatic periapical lesions in group A while in group B (control group) no intracanal medicament will be placed. Patients will be randomly divided into two groups by randomization in Statistical Package for Social Sciences software (SPSS v24.0). They will be recalled for one week and three week follow ups and in case of no clinical signs and symptoms endodontic procedure will be completed. Statistical analysis: Descriptive statistics will be used for reporting age. Frequencies and percentages will be calculated for categorical variables and intergroup comparison will be done by chi square test
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Intervention Group | Experimental | Fresh AVG will be prepared. It will be placed as intracanal medicament after cleaning and shaping in patients with asymptomatic periapical lesions |
|
| Control Group | No Intervention | No intracanal medicament will be placed |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Aloe vera Gel | Biological | A fresh aloe vera (Aloe Barbadensis) leaf will be plucked from the plant. The leaf will be washed with normal saline, peeled with scalpel and the inner gel will be blended in a blender to convert it into a watery consistency. The solution will be stored in an autoclaved flask. |
| Measure | Description | Time Frame |
|---|---|---|
| Presence or absence of signs and symptoms of the patient | Patients in both the groups will be recalled after one week. They will be assessed clinically for either presence or absence of signs and symptoms.
| One week and 3 weeks |
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Inclusion Criteria:
Exclusion Criteria:
History of allergy to AVG
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| Name | Affiliation | Role |
|---|---|---|
| Saima Azam, BDS,FCPS | Islamabad Dental Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Islamabad Dental Hospital | Islamabad | Federal | 44000 | Pakistan |
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| ID | Term |
|---|---|
| D010483 | Periapical Diseases |
| D012816 | Signs and Symptoms |
| ID | Term |
|---|---|
| D007571 | Jaw Diseases |
| D009057 | Stomatognathic Diseases |
| D010510 | Periodontal Diseases |
| D009059 | Mouth Diseases |
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| ID | Term |
|---|---|
| C586178 | Aloe vera gel |
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|
| D013568 |
| Pathological Conditions, Signs and Symptoms |