Ordered Eating and Acute Exercise | NCT06242015

Studies
Ordered Eating and Acute Exercise

NCT06242015

Sponsor

Old Dominion University

Status

Completed

Last Update Posted

Aug 1, 2025Actual

Enrollment

23Actual

Phase

Not Applicable

Conditions

Glucose Metabolism Disorders
Hunger

Interventions

Carbohydrate-first meal
Carbohydrate-last meal

Countries

United States

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Jul 2025

Overall Recruitment Status or Expanded Access Status

Completed

Last Known Status

Not provided

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Feb 6, 2024Actual

Primary Completion Date

Jul 30, 2024Actual

Completion Date

Jul 30, 2024Actual

First Submitted Date

Jan 28, 2024

First Submission Date that Met QC Criteria

Jan 28, 2024

First Posted Date

Feb 5, 2024Actual

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Jul 29, 2025

Last Update Posted Date

Aug 1, 2025Actual

Sponsor/Collaborators Module

Responsible Party, by Official Title

Patrick Wilson, PhD, Associate Professor of Exercise Science, Old Dominion UniversityPrincipal Investigator

Lead Sponsor

Old Dominion UniversityOTHER

Collaborators

Not provided

Oversight Module

Has Data Monitoring Committee (DMC)

Is FDA Regulated Drug

Is FDA Regulated Device

Is Unapproved Device

Not provided

Pediatric Postmarket Surveillance of a Device Product

Not provided

Product Exported from US

FDAAA801 Violation

Not provided

Description Module

Brief Summary

There is well documented evidence that ingesting dietary carbohydrate in large amounts tends to increase postprandial glucose. In healthy populations, this is not necessarily a problem, but continuous exposure to high levels of glucose-hyperglycemia-is a defining characteristic and risk factor for type 2 diabetes mellitus. Consuming a carbohydrate-rich food as the final food in a meal sequence has been shown to significantly reduce postprandial glucose excursions in both diabetes patients and in healthy controls. The exact mechanisms behind this phenomenon are not well understood, but one proposed course is simply that the vegetable and protein already being digested slows the rate of glucose rise.

Despite the findings, little-to-no research has examined how manipulating the order of foods in a meal impacts subsequent exercise responses. In this experimental crossover study, each participant will undergo two acute feeding conditions (carbohydrate-rich foods first vs. last in a meal), which will be followed by exercise 60 minutes later. We will observe the effects of meal order on postprandial glucose, substrate/fuel utilization, and subjective perceptions at rest and during 30 minutes of exercise.

Detailed Description

Not provided

Design Module

Study Type

Interventional

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Not provided

Target Follow-Up Duration

Not provided

Phases

Not Applicable

Interventional Study Design

Allocation

Biospecimen

No data available

No data is available for this block.

Enrollment

23Actual

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
Carbohydrate-first meal	Experimental		Other: Carbohydrate-first meal
Carbohydrate-last meal	Experimental		Other: Carbohydrate-last meal

Interventions

Name	Type	Description	Arm Group Labels	Other Names
Carbohydrate-first meal	Other	Rice (150 grams) eaten first, followed by broccoli (150 grams) and chicken (100 grams)	Carbohydrate-first meal

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Postprandial glucose	Blood glucose will be measured with fingerstick samples and a portable glucometer	2 hours (premeal and 30, 60, 90, and 120 minutes after eating)

Secondary Outcomes

Measure	Description	Time Frame
Carbohydrate use	Carbohydrate utilization will be estimated from respiratory gas exchange	100 minutes (premeal and continuously for 90 minutes after eating)
Fat use	fat utilization will be estimated from respiratory gas exchange

Other Outcomes

Not provided

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

Currently physically active (scheduled exercise at least three days per week for 30 minutes each time over the last three months)
Ability to perform moderate-to-high intensity running for at least 30 minutes

Exclusion Criteria:

Any allergy or other condition that would prohibit the consumption of poultry, rice, or broccoli
Any injury or disease (cardiovascular disease, diabetes, pulmonary disease except controlled asthma) precluding physical exercise
Currently pregnant
Implanted electrical devices such as a pacemaker.

Accepts Healthy Volunteers

Yes

Sex

All

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

18 Years

Maximum Age

60 Years

Standard Ages

Adult

Study Population

Not provided

Sampling Method

Not provided

Contacts/Locations Module

Central Contacts

Not provided

Overall Officials

Name	Affiliation	Role
Patrick Wilson	Old Dominion University	Principal Investigator

Locations

Facility	Status	City	State	ZIP	Country	Contacts
ODU Human Performance Laboratory		Norfolk	Virginia	23529	United States

IPD Sharing Statement Module

Plan to Share IPD

Yes

Description

De-identified IPD will be shared upon reasonable request. Requests should be made to the corresponding author.

Types

Not provided

Time Frame

The data will be made available upon the study's publication and will remain available for at least 5 years

Access Criteria

Researchers with a justified reason for wanting access to the data

URL

Not provided

Condition Browse Module

MeSH Terms

ID	Term
D044882	Glucose Metabolism Disorders
D009043	Motor Activity

Ancestor Terms

ID	Term
D008659	Metabolic Diseases
D009750	Nutritional and Metabolic Diseases
D001519	Behavior

Browse Leaves

Not provided

Browse Branches

Not provided