Optic Nerve Head Strain as Biomarker for Glaucoma

Optic Nerve Head Strain as Biomarker for Glaucoma

The investigators will test the hypothesis that images of the optic nerve head taken a 2 different eye pressures will yield strain estimates that are predictive of the course of glaucoma.

Existing glaucoma patients and suitable control adults will be imaged with an FDA-approved optical coherence tomography instrument. Those who are imaged at 2 different eye pressures will generate biomechanical strain estimates. These will be compared to visual field and retinal nerve fiber layer measurements over time. The investigators expect that baseline strain and their changes over time will be associated with progression rate of glaucoma damage, providing a biomarker for susceptibility.

Inclusion Criteria:

• Existing glaucoma patients of Johns Hopkins

Exclusion Criteria:

• Inability to perform imaging
• illiterate
• hearing impaired
• non-English speakers