Retrospective study focusing on the diagnosis and treatment outcomes of pituitary adenomas

evaluate pathological type and treatment effect after treatment

The pituitary adenoma recurred 1 year after treatment. The recurrence was assessed by 3 aspects: (1)contrast enhanced MRI showed suspicious tumor growth, such as bone destruction; (2)signs and symptoms that had disappeared after treatment reappeared, such as pressing on nearby nerve tissue and some characteristic appearance; (3)endocrine indexes rose again after reaching the remission standard, iculding Prolactin(PRL)>30 μg/L in Lactotroph adenoma; growth hormone (GH)>2.5ng/ml in Somatotroph adenoma, serum cortisol>800nmol/L at 8am in Corticotroph adenoma, while other types do not consider endocrine indicators.

The pathological examination was used to evaluated the type of pituitary adenoma. The pathological type was assessed by 2017 WHO standard, divided into Somatotroph adenoma, Lactotroph adenoma, Thyrotroph adenoma, Corticotroph adenoma, Gonadotroph adenoma, Null-cell adenoma and Plurihormonal and double adenomas.