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SHAG is a text messaging-based HIV prevention program designed for cisgender sexual minority boys and men 13-20 years of age across the United States. Investigators will test it against a control group that receives messages about healthy lifestyle.
SHAG is a text messaging-based HIV prevention program designed for cisgender sexual minority boys and men 13-20 years of age across the United States. Investigators will test it against a control group that receives messages about healthy lifestyle. Harnessing the power of technology, young people will be recruited online and largely enrolled digitally. The main outcome of interest is HIV incidence. The impact of the intervention on STI testing and pre-exposure prophylaxis (PrEP) will also be examined.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| SHAG (Sexual Health Advocacy for Guys) | Experimental | Young people assigned to the intervention arm will receive ~9 weeks of daily text messages that talk about healthy sexuality and ways to reduce HIV risk. After a 3 month 'quiet' period, they will receive a week of review messages. Messages are based upon the information-motivation-behavioral model of preventive behavior. |
|
| Attention-matched control | Placebo Comparator | Young people assigned to the control arm will receive ~9 weeks of daily text messages that talk about healthy lifestyle, such as self-esteem and physical exercise. After a 3 month 'quiet' period, they will receive a week of review messages. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Sexual health advocacy for guys | Behavioral | 5 month HIV prevention program delivered via text messaging |
|
| Measure | Description | Time Frame |
|---|---|---|
| HIV Incidence | HIV Incidence determined by home testing kit | 12-months post-intervention and immediately post-intervention |
| Measure | Description | Time Frame |
|---|---|---|
| Self-reported HIV incidence | Self-reported HIV Status | Post-Intervention, 3-months post, 6-months post, 9-months post, 12-month post |
| Proportion of Participants Testing for an STI | This outcome will be measured as a cumulative indicator of whether the individual has tested for an STI |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Center for Innovative Public Health Research | Recruiting | San Clemente | California | 92672-6745 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 39762976 | Derived | Ybarra ML, Feaster DJ, Garofalo R, Bull S. Sexual Health Advocacy for Guys (SHAG): a randomized trial of the impact of a text-messaging program on HIV incidence and STI testing among a national sample of sexual minority cisgender adolescent and young adult men. Trials. 2025 Jan 6;26(1):9. doi: 10.1186/s13063-024-08540-9. |
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Individual-level de-identified data will be made available through controlled access.
Data will be available starting 12 months after the grant ends.
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| ID | Term |
|---|---|
| D015658 | HIV Infections |
| ID | Term |
|---|---|
| D000086982 | Blood-Borne Infections |
| D003141 | Communicable Diseases |
| D007239 | Infections |
| D015229 | Sexually Transmitted Diseases, Viral |
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Participants will be randomized to either the intervention or control group
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Control group content is written to affect an experience as if one were in the intervention group.
| Healthy lifestyle control | Behavioral | 5 month control group program delivered via text messaging |
|
| 12-month post intervention and immediately post-intervention |
| Proportion of Participants having used PrEP/PEP | This outcome will be measured as a cumulative indicator of whether the individual has used pre-exposure or post-exposure prophylaxis for HIV | 12-month post-Intervention and immediately post-intervention |
| Center for Innovative Public Health Research | Recruiting | San Clemente | California | 92672 | United States |
|
| D012749 | Sexually Transmitted Diseases |
| D016180 | Lentivirus Infections |
| D012192 | Retroviridae Infections |
| D012327 | RNA Virus Infections |
| D014777 | Virus Diseases |
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
| D007153 | Immunologic Deficiency Syndromes |
| D007154 | Immune System Diseases |