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The goal of this observational study is to compare laparoscopic and open surgery outcomes in colorectal cancer patients with BMI ≥ 30 kg/m2 . The main question[s] it aims to answer are:
This study is a retrospective and observational study. Subjects were not be given or offered any treatment during the study. The investigator reviewed the patient's medical history and examination report to determine eligibility based on inclusion and exclusion criteria.
If there is a comparison group: Researchers compared the open group and laparoscopy group to see if the laparoscopic group have better short-term outcomes with comparable oncologic outcomes to the open group.
This study is a retrospective and observational study. Subjects were not be given or offered any treatment during the study. The investigator reviewed the patient's medical history and examination report to determine eligibility based on inclusion and exclusion criteria.
Given the uncertainty regarding the long-term outcomes of laparoscopy in obese patients with CRC, this study aimed to analyse a decade of data comparing laparoscopic and open surgery outcomes in patients with BMI ≥ 30 kg/m2 who had undergone treatment for CRC at the Linkou Chang Gung Hospital.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Laparoscopic Group | Individuals with a body mass index of ≥ 30 kg/m2 underwent laparoscopic surgery for primary stage I-III colorectal adenocarcinoma. | ||
| Open Group | Individuals with a body mass index of ≥ 30 kg/m2 underwent open surgery for primary stage I-III colorectal adenocarcinoma. |
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| Measure | Description | Time Frame |
|---|---|---|
| Short-term outcome | Postoperative mortality risk | 2009 to 2019 |
| Short-term outcome | Postoperative morbidity risk | 2009 to 2019 |
| Short-term outcome | Clavien-Dindo classification | 2009 to 2019 |
| Short-term outcome | Length of hospital stay | 2009 to 2019 |
| Short-term outcome | Incidence of readmission | 2009 to 2019 |
| Measure | Description | Time Frame |
|---|---|---|
| Long-term Oncologic outcome | Disease-free survival (DFS) | 2009 to 2019 |
| Long-term Oncologic outcome | Overall survival (OS) | 2009 to 2019 |
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Inclusion Criteria:
Exclusion Criteria:
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Stage I ~ III Colorectal adenocarcinoma patients with BMI ≥ 30 kg/m2 who underwent colorectal surgery at the Linkou branch of the Chang Gung Memorial Hospital (CGMH) between January 2009 and December 2019.
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 38833348 | Derived | Hsu YJ, Yu YL, Jhuang JR, You JF, Liao CK, Tsai WS, Pan YP, Chern YJ. Comparison of laparoscopic and open surgery for colorectal malignancy in obese patients: a propensity score-weighted cohort study. Int J Surg. 2024 Aug 1;110(8):4598-4607. doi: 10.1097/JS9.0000000000001536. |
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The data that support the findings of this study are available from the corresponding author upon reasonable request
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| ID | Term |
|---|---|
| D015179 | Colorectal Neoplasms |
| D009765 | Obesity |
| ID | Term |
|---|---|
| D007414 | Intestinal Neoplasms |
| D005770 | Gastrointestinal Neoplasms |
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
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| Long-term Oncologic outcome | Recurrence rate | 2009 to 2019 |
| D009369 | Neoplasms |
| D004066 | Digestive System Diseases |
| D005767 | Gastrointestinal Diseases |
| D003108 | Colonic Diseases |
| D007410 | Intestinal Diseases |
| D012002 | Rectal Diseases |
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
| D001835 | Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |