A Study on the Prophylactic Use of Antibiotics Within 72 Hours After Acute Burn Injury in Patients

A Prospective Randomized Controlled Study on the Prophylactic Use of Antibiotics Within 72 Hours After Acute Burn Injury in Patients

The goal of this clinical trial is to compare in acute burn patients.

The main question it aims to answer are:

• what is the impact of early prophylactic use of antibiotics on prognosis Participants will be randomly divided into an antibiotic group and a non antibiotic group.

Researchers will compare the two groups to see the 72 hour wound bacterial culture negative rate.

Inclusion Criteria:

• Signed and dated informed consent form
• Promise to comply with research procedures and cooperate with the implementation of full process research
• Age 18 and above
• Emergency hospitalization of patients in the burn department, within 24 hours after injury
• No immunodeficiency disease, no history of using immunosuppressive drugs, no antibiotics being used or infectious diseases at the time of admission
• If a woman is in the reproductive period, she should not be pregnant

Exclusion Criteria:

• Unable to obtain informed consent from subjects, family members, or authorized agents
• At the time of admission, antibiotics were being administered
• During pregnancy
• Presence of infectious diseases before admission
• Existence of immunodeficiency diseases or use of immunosuppressive drugs
• The subjects are currently undergoing other clinical studies