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This study is a single-arm, prospective, multicenter, observational registry study. It plans to enroll 120 migraine patients who meet the inclusion criteria and are treated with rimegepant in selected hospital outpatient clinics in the Greater Bay Area. The main purpose of this study is to observe the effectiveness of rimegepant in treating migraines in a real-world clinical setting, including the impact of rimegepant on the quality of life, functioning, productivity status of migraine patients, and patients' satisfaction with the use of rimegepant in treating migraines.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Rimegepant | Drug | No intervention. The study will record the usage, timing, frequency, and dosage of rimegepant in a real-world clinical setting. |
| Measure | Description | Time Frame |
|---|---|---|
| Treatment Satisfaction Questionnaire for Medication (TSQM) | Treatment Satisfaction Questionnaire for Medication (TSQM) score for migraine patients' satisfaction with treatment of rimegepant | 4 weeks |
| European Quality of Life-5 Dimensions-5 Levels (EQ-5D-5L) | European Quality of Life-5 Dimensions-5 Levels (EQ-5D-5L) score for the impact of rimegepant on the quality of life of migraine patients | 4 weeks |
| Headache Impact Test-6 (HIT-6) | Headache Impact Test-6 (HIT-6) score for the impact of rimegepant on the functioning of migraine patients | 4 weeks |
| Work Productivity and Activity Impairment-General Health (WPAI-GH) | Work Productivity and Activity Impairment-General Health (WPAI-GH) score for the impact of rimegepant on the productivity and work efficiency of migraine patients | 4 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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Consecutively enroll 120 migraine patients who meet the inclusion criteria and are receiving treatment with rimegepant in selected outpatient clinics in the Guangdong-Hong Kong-Macao Greater Bay Area
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University | Guangzhou | Guangdong | 510120 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41204073 | Derived | Wang J, Jiang J, Peng S, Jiang J, Liu Z, Cai J, Li J, Li Y, Chen Y, Li H, Rong X, He L, Ren L, Ji Y, Li S, Zhu Y, Xiao S, Tang Y, Xu Y. Patient-reported outcomes of rimegepant for acute and preventive treatment of migraine in China: a prospective, multicenter, real-world study. J Headache Pain. 2025 Nov 7;26(1):242. doi: 10.1186/s10194-025-02197-8. |
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| ID | Term |
|---|---|
| D008881 | Migraine Disorders |
| ID | Term |
|---|---|
| D051270 | Headache Disorders, Primary |
| D020773 | Headache Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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| ID | Term |
|---|---|
| C578443 | rimegepant sulfate |
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| D009422 | Nervous System Diseases |