Capsule Endoscopy in Iron Deficiency Anaemia

Diagnostic Yield of Video Capsule Endoscopy for Iron Deficiency Anaemia

This project aim to investigate whether wireless capsule endoscopy(WCE) has a similar diagnostic yield as conventional endoscopy in detecting the cause of iron deficiency anemia (IDA)

IDA is common and 90-95% of cases are caused by bleeding from ulcers, tumours or vascular malformations in the oesophagus, stomach, duodenum, small intestine or the large bowel.Bleeding from more than one localisation is common.

International guidelines recommend bidirectional endoscopy(gastro- and colonoscopy) to detect and treat the source of bleeding.

Our hypothesis is that WCE is non-inferior to the combination of gastroscopy and colonoscopy in locating GI-bleeding and that complete examinations will be achieved in ≥90% of the examinations.

Inclusion Criteria:

• Referred to flexible endoscopy for a verified Iron Deficiency Anaemia

Exclusion Criteria:

• Unwillingness to participate
• Not able to provide informed consent
• Not understanding the instructions
• Severe cardio-vascular disease New York Heart Association III-IV
• Symptoms of bowel obstruction/previous bowel obstruction
• Bowel surgery except for end to end anastomosis in the colon
• Pregnancy