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To compare the clinical and postoperative analgesic effects of hydromorphone combined with ropivacaine and ropivacaine alone in quadrangular muscle block for open inguinal hernia in elderly patients.
Elderly patients selected for Lichtenstein hernia repair in our hospital who met the inclusion and exclusion criteria and obtained informed consent were included in this trial, and were randomly divided into experimental group by random number table method: 0.375% ropivacaine combined with hydromorphone block group, and control group: 0.375% ropivacaine block group alone.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Hydromorphone combined with ropivacaine | Experimental | The posterior quadrat block was performed by adding 1mg hydromorphone to 0.375% ropivacaine in a total of 30ml. |
|
| ropivacaine | Active Comparator | A mixture of 0.375% ropivacaine for a total of 30ml was performed for posterior quadrate block. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Hydromorphone combined with ropivacaine | Drug | 1mg hydromorphone was added to 0.375% ropivacaine for a total of 30ml to perform quadrat block |
|
| Measure | Description | Time Frame |
|---|---|---|
| Related indexes of anesthesia effect: pain after surgery, 6, 12, 18,24, 48h after surgery. | Visual analogue scale (VAS) was used to score the postoperative pain at 6,12,18,24,48h.The score ranges from 0 (no pain) to 10 (most severe pain). The change was equal to the score difference between the two groups at different observation time points (6,12,18,24,48h). | From the end of surgery until two days after surgery. |
| Related indexes of anesthesia effect: time of onset of anesthesia, duration of anesthesia maintenance. | The range of the effective time of anesthesia minus the start time of anesthesia and the maintenance time minus the start time of anesthesia are respectively.The unit of time is minutes. | From the start of anesthesia until two days after surgery. |
| Measure | Description | Time Frame |
|---|---|---|
| The occurrence of postoperative adverse reactions. | The rates of postoperative nausea, vomiting and dizziness were compared between the two groups. | The operation ended two days after surgery. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Dan Tian | Second Hospital of Jilin University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Second Hospital of Jilin University | Changchun | Jilin | 130000 | China |
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| ID | Term |
|---|---|
| D006552 | Hernia, Inguinal |
| ID | Term |
|---|---|
| D046449 | Hernia, Abdominal |
| D006547 | Hernia |
| D020763 | Pathological Conditions, Anatomical |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D000077212 | Ropivacaine |
| ID | Term |
|---|---|
| D000813 | Anilides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D000814 | Aniline Compounds |
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|
| Ropivacaine | Drug | A mixture of 0.375% ropivacaine for a total of 30ml was used for quadrate block |
|
|
| D000588 |
| Amines |