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| ID | Type | Description | Link |
|---|---|---|---|
| 82201158 | Other Grant/Funding Number | National Natural Science Foundation of China |
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In modern cataract surgery, residual astigmatism continues to be one of the major factors influencing patients' visual quality and satisfaction. The goal of this study is to compare the clinical outcomes of femtosecond laser arcuate keratotomy in one eye and Toric intraocular lens implantation in the contralateral eye for astigmatism correction in patients undergoing femtosecond laser-assisted cataract surgery. The study is a prospective randomized comparative study. Patients with binocular regular corneal astigmatism ranging from 0.75 to 3.00 D will be recruited. The patient will randomly receive femtosecond laser arcuate keratotomy in one eye and receive Toric intraocular lens implantation in the contralateral eye. Long term evaluation will be performed to compare the visual acuity, subjective manifest refraction, and corneal topography between groups.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Femtosecond laser arcuate keratotomy | Active Comparator | femtosecond laser arcuate keratotomy will be designed using Donnenfeld nomogram. |
|
| Toric intraocular lens implantation | Active Comparator | The Toric IOL power and alignment axis were calculated using the online calculator available at https://www.tecnistoriccalc.com |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Femtosecond laser arcuate keratotomy | Procedure | The patient will receive femtosecond laser arcuate keratotomy and femtosecond laser-assisted cataract surgery with implantation of a monofocal intraocular lens in one eye. |
| Measure | Description | Time Frame |
|---|---|---|
| Refractive astigmatism | subjective manifest refraction and residual astigmatism | 1 day, 1 week, 1 month, 3 months and 1year postoperatively |
| Measure | Description | Time Frame |
|---|---|---|
| Visual acuity | uncorrected distance visual acuity and corrected distance visual acuity | 1 day, 1 week, 1 month, 3 months and 1year postoperatively |
| Measure | Description | Time Frame |
|---|---|---|
| Keratometric astigmatism | Corneal topography measurement | 1 day, 1 week, 1 month, 3 months and 1year postoperatively |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Yueyang Zhong | Contact | +8618868125901 | yyzbzhong@zju.edu.cn |
| Name | Affiliation | Role |
|---|---|---|
| Ke Yao | Second Affiliated Hospital, School of Medicine, Zhejiang University | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Eye Center of the Second Affiliated Hospital of Zhejiang University | Recruiting | Hangzhou | Zhejiang | 310009 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33795782 | Background | Noh H, Yoo YS, Shin KY, Lim DH, Chung TY. Comparison of penetrating femtosecond laser-assisted astigmatic keratotomy and toric intraocular lens implantation for correction of astigmatism in cataract surgery. Sci Rep. 2021 Apr 1;11(1):7340. doi: 10.1038/s41598-021-86763-5. | |
| 26352561 | Background | Yoo A, Yun S, Kim JY, Kim MJ, Tchah H. Femtosecond Laser-assisted Arcuate Keratotomy Versus Toric IOL Implantation for Correcting Astigmatism. J Refract Surg. 2015 Sep;31(9):574-8. doi: 10.3928/1081597X-20150820-01. |
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There is not a plan to make IPD available.
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| Toric intraocular lens implantation | Procedure | The patient will receive femtosecond laser-assisted cataract surgery with implantation of a Toric monofocal intraocular lens in the contralateral eye. |
|
| ID | Term |
|---|---|
| D002386 | Cataract |
| D001251 | Astigmatism |
| ID | Term |
|---|---|
| D007905 | Lens Diseases |
| D005128 | Eye Diseases |
| D012030 | Refractive Errors |
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