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The goal of this open-label randomized controlled trial is to explore the benefit of limb elevation in inpatient gout flare episodes, compared with standard treatment The main questions are;
Participants will be divided into 2 group;
Pain score and joint circumference will be recored at recruitment, 24 hour and 48 hour
Limb elevation has shown benefit in ankle sprain and venous insufficiency, but its benefit has not been studied in people with gout flare. In this open-label randomized controlled trial, 30 adults diagnosed with gout flare during their hospitalization will be randomized to receive limb elevation plus standard medication for gout flare (limb elevation group) or standard medication only (control group). Primary outcome is reduction in 10-point visual analogue scale for pain at 48 hours after enrollment and the secondary outcome is the reduction of the circumference of affected joint at 48 hours after enrollment. Comparison of pain score and joint circumference reduction will be made using Wilcoxon Rank-sum test. Our study results may provide some evidence in support of limb elevation as a supplementary non-pharmacological therapy for relief of gout flare.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| limb elevation group | Experimental | limb elevation plus standard medication |
|
| control group | No Intervention | standard medication only |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| limb elevation | Procedure | limb elevation more than 45 degrees |
|
| Measure | Description | Time Frame |
|---|---|---|
| Reduction of pain score | 10-points Visual Analogue Scale | 48 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Joint circumference | circumference of affected joint in centimeter | 48 hours |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| RatchayaSaitip Lertnawapan | Contact | 0973941619 | ratchas@yahoo.com | |
| kanon jatuworapruk | Contact | 029269794 | kanon@tu.ac.th |
| Name | Affiliation | Role |
|---|---|---|
| saitip sangkamanovet | Thammasat University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Thammasat University | Pathum Thani | 12120 | Thailand |
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| ID | Term |
|---|---|
| D006073 | Gout |
| D001168 | Arthritis |
| ID | Term |
|---|---|
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
| D000070657 | Crystal Arthropathies |
| D012216 | Rheumatic Diseases |
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| D011686 |
| Purine-Pyrimidine Metabolism, Inborn Errors |
| D008661 | Metabolism, Inborn Errors |
| D030342 | Genetic Diseases, Inborn |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |