Cardiac Amyloidosis in HFpEF Tunisian Patients

Prevalence of Cardiac Amyloidosis in Heart Failure Patients With Preserved Left Ventricular Ejection Fraction in Tunisia

Cardiac amyloidosis (CA) has recently been reported as a common cause of heart failure with preserved left ventricular ejection fraction (HFpEF), with a prevalence of 6% in elderly HFpEF patients. However, the diagnosis of CA is still challenging and requires multiple costly investigations.

Regardless of the type of CA, TTR or AL, early diagnosis significantly improves prognosis.

In this study, the investigators aimed to determine the prevalence of CA in Tunisian HFpEF patients and to identify clinical and ultrasound criteria predictive of CA.

Inclusion Criteria:

• HFpEF during the previous year
• IVS thickness of 12mm or greater

Exclusion Criteria:

• age under 60 years
• Acute coronary syndrome complicated by HFpEF
• Congenital heart disease