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The rising prevalence fof fetal macrosomia represents a significant challenge in obstetrics, affecting both maternal and neonatal outcomes. Such challenges include complications like perineal tears and postpartum hemorrhage. Concurrently, the frequency of labor induction practices on the rise, yet the implications for neonatal weight are inadequately understood. To address this gap, our study aims to evaluate the association between labor induction and neontal birth weight through a population-based cohort study. The findings have the potential to inform more accurate clinical guidelines, thereby enhancing the quality of maternity care.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| induction of labor | Patient having been induced by cervical ripening (prostin gel (2mg/24h), intravaginal prostaglandin (10mg/24h), balloon (<12h exposure time) or oral misoprostole (50µg/4h until induction of labor) or induction of contractions by oxytocin (gradual increase in dose) for suspected ultrasound macrosomia (according to the criteria of the DAME study) | ||
| natural labor | Patient presenting with spontaneous labor after 37 weeks of gestation. |
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| Measure | Description | Time Frame |
|---|---|---|
| Number of vaginal deliveries among the population studied | Number of vaginal deliveries among the population studied | during Delivery |
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Inclusion Criteria:
Exclusion Criteria:
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The selected patients are thoses who gave birth at term (>37 weeks) of a macrosome fetus (>4000g) in one of the maternity wards of the civil hospices of Lyon (Hospital de la Croix Rousse, Hopital Femme Mere Enfant or Hopital Lyon Sud). Patients are subsequently categorized based on whether their labor was induced or not. The characteristics of the pregnancy, the route of delivery and the fetal outcome are then collected in the computerized medical records and analyzed.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hôpital Femme-Mère-Enfant | Bron | 69500 | France | |||
| Croix Rousse Hospital |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 42045843 | Derived | Mazard A, Desseauve D, Boulvain M, Atallah A, Massoud M, Gaucher L, de la Fourniere B. Mode of delivery for confirmed macrosomia: a real-life multicentric observational study. BMC Pregnancy Childbirth. 2026 Apr 27;26(1):640. doi: 10.1186/s12884-026-09090-5. |
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| ID | Term |
|---|---|
| D001724 | Birth Weight |
| D005320 | Fetal Macrosomia |
| D006470 | Hemorrhage |
| ID | Term |
|---|---|
| D001835 | Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D016640 | Diabetes, Gestational |
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| Lyon |
| 69004 |
| France |
| Hôpital Lyon Sud | Pierre-Bénite | 69495 | France |
| D011248 | Pregnancy Complications |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D005315 | Fetal Diseases |
| D011254 | Pregnancy in Diabetics |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D048909 | Diabetes Complications |
| D003920 | Diabetes Mellitus |
| D004700 | Endocrine System Diseases |
| D010335 | Pathologic Processes |