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This study will be conducted to investigate the following:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| GVS group | Experimental | Galvanic Vestibular Stimulation in addition to the Conventional Physical Therapy program of moderate intensity aerobic training on cyclic ergometer for upper limb and task oriented training for hand dexterity. |
|
| CPT group | Active Comparator | Conventional Physical Therapy program of moderate intensity aerobic training on cyclic ergometer for upper limb and task oriented training for hand dexterity. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Galvanic vestibular stimulation | Device | galvanic current generated by Gymna DUO 200 and delivered through conductive medium (electrode gel) by two small carbon rubber electrodes 3 cm 2 each bilaterally over two mastoid processes for 30 minutes, two times per week for 12 weeks . |
| Measure | Description | Time Frame |
|---|---|---|
| Cortical changes | central motor conduction time is the time taken for neural impulses to travel through the central nervous system on their way to the target muscles. | 15 minutes |
| Upper Limb motor dexterity | Nine hole peg test 9 HPT | 15-20 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| Advanced dexterity (Handwriting analysis) by MovAlyzeR® software | 15-20 minutes | |
| Balance | Berg Balance scale (BBS) of 14 items graded on 5 scoring system 0= worst and 4= the best ( total 0 = worst performance - Total 56 = Best performance). The lower your score, the more at risk you are for losing your balance. In general, Berg balance scale scores are interpreted as such: 0 to 20: A person with a score in this range will likely need the assistance of a wheelchair to move around safely. |
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Inclusion Criteria:
Exclusion Criteria:
Patients will be excluded if they have:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Cairo University | Recruiting | Cairo | Egypt |
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| MovAlyzeR® software from Neuroscript | Device | MovAlyzeR® movement analysis software from Neuroscript turns a pen tablet or mouse into a high-quality system for examining movements by a pen, mouse or finger. Hence, it can train and analyze hand dexterity and handwriting using pen tablets such as sentence parameters. |
|
| BODYFIT Mini Portable Pedal Home Exerciser (cyclic ergometer) | Device | stationary upper body pedaling as a moderate intensity aerobic training |
|
| 15-20 minutes |
| Fatigue | Fatigue Severity Scale (FSS)is 9-item questionnaire, scored on a 7 point scale with 1 = strongly disagree and 7= strongly agree. The minimum score = 9 and maximum score possible = 63. Higher the score = greater fatigue severity. | 15-20 minutes |
| ID | Term |
|---|---|
| D009103 | Multiple Sclerosis |
| ID | Term |
|---|---|
| D020278 | Demyelinating Autoimmune Diseases, CNS |
| D020274 | Autoimmune Diseases of the Nervous System |
| D009422 | Nervous System Diseases |
| D003711 | Demyelinating Diseases |
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |
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