The purpose of the study is to evaluate the influence of needle size, injected fluid volume, and rate of fluid on the degree of pain experienced by adult healthy volunteers after subcutaneous infusion of sterile saline.

Inclusion Criteria:

• Body Mass Index greater than (>)18 and less than (<) 36
• Able to understand the English language
• Has a negative coronavirus-2019 (COVID-19) test result at the time of admission, prior to administration of study intervention

Exclusion Criteria:

• Age < 18 years and > 60 years
• BMI < 18 or > 36
• Unable to understand the English language
• Currently pregnant or lactating
• History of skin sensitivity or allergy to steel needle or adhesive tape
• History of abnormal blood coagulation or bleeding
• History of abnormal immune function or frequent skin infections
• Active cardiovascular, pulmonary, dermatologic, endocrine, rheumatologic, hematologic, ophthalmologic, psychiatric, metabolic, hepatic, renal, immune, gastrointestinal, neurological, or musculoskeletal disease
• Has tattoo(s) or scarring at the site of injection or any other condition which may interfere with the injection site examination, in the opinion of the investigator

The data sharing policy of the Janssen Pharmaceutical Companies of Johnson & Johnson is available at www.janssen.com/clinical-trials/transparency. As noted on this site, requests for access to the study data can be submitted through Yale Open Data Access (YODA) Project site at yoda.yale.edu