Aim: The aim of this study is to evaluate the action of the homeopathic plant Arnica Montana on postoperative edema, pain and trismus after surgical extraction of impacted wisdom teeth.

Materials and Methods: The study is a double-blinded clinical trial recruiting patients undergoing surgical extraction of symmetrically impacted maxillary or mandibular third molars (right and left side). Patients receive alternately and randomly the verum (Arnica Montana 12 CH) or the placebo, in the form of capsules, to be taken 1 day prior to surgery and for 7 days postoperatively. Clinical parameters are collected and include: pain score, maximum mouth opening and facial measurements to assess edema's intensity.

Inclusion Criteria:

• Symmetrically impacted bilateral third molars (mandibular or maxillary).
• Young patients aged between 16 and 40 years old.
• No consumption of tobacco or coffee.
• Consent to the terms and conditions of the study.
• Good oral hygiene.
• ASA 1.

Exclusion Criteria:

• Not symmetrically impacted third molars
• Patients with health problems