Effects of Marijuana on Neuropathic Pain and Spasticity in Spinal Cord Injury Patients

Effects of Marijuana on Neuropathic Pain and Spasticity in Spinal Cord Injury Patients

The goal of this clinical trial is to compare effects of marijuana or cannabis on neuropathic pain and spasticity in spinal cord injury patients. The main question is: Does the cannabis product from KhonKaen University reduce neuropathic pain and spasticity in spinal cord injury patients? The research design is a crossover study. The participants will be randomly into 2 groups: group 1 and group 2. The participants received either cannabis or placebo for 2 weeks. After completing treatment, participants were swapped to the other group for 2 weeks, a wash-out period is 2 weeks. The outcome measurements are pain and spasticity.

Inclusion Criteria:

• Spinal cord injury more than 6 months
• Neuropathic pain
• Pain score > 3
• Do not response to standard medical treatment
• Given inform consent

Exclusion Criteria:

• Allergy to cannabis
• Unstable cardiovascular and pulmonary diseases
• Chronic kidney and liver diseases
• Psychological disease
• Pregnancy or breastfeeding