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The purpose of this study is to evaluate the efficiency and toxicity of adjuvant hypofractionation radiotherapy for thymic epithelial tumours after complete resection.
Adjuvant Radiotherapy(Postoperative radiotherapy) is proposed in stage II and III thymic carcinoma，stage III thymoma，stage IIB B2/B3 thymomas.
Hypofractionation Radiotherapy is used in this study. The purpose of this study is to evaluate the efficiency and toxicity of adjuvant hypofractionation radiotherapy for thymic epithelial tumours after complete resection.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Adjuvant Hypofractionation Radiotherapy | Experimental | Adjuvant Hypofractionation Radiotherapy for Thymic Epithelial Tumours After Complete Resection |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Adjuvant Hypofractionation Radiotherapy | Radiation | Adjuvant Hypofractionation Radiotherapy for Thymic Epithelial Tumours After Complete Resection |
|
| Measure | Description | Time Frame |
|---|---|---|
| Disease Free Survival | From the date of resection to the date of disease recurrence or death | 2 years, 5 years |
| Measure | Description | Time Frame |
|---|---|---|
| Overall Survival | From the date of resection to the date of death | 2 years, 5 years |
| RadiotherapyToxicity | Rate of pneumonitisï¼›Rate of esophagitisï¼›Rate of skin reactionï¼›Rate of myelitisï¼›Rate of heart diseaseï¼›Rate of vascular toxicity |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Tao Zhang, Dr. | National Cancer Center/Cancer Hospital, CAMS | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| National Cancer Center/Cancer Hospital, Chinese Academy of Medical Science and Peking Union Medical College | Beijing | Beijing Municipality | 100021 | China |
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| ID | Term |
|---|---|
| D013953 | Thymus Neoplasms |
| ID | Term |
|---|---|
| D013899 | Thoracic Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D008206 | Lymphatic Diseases |
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Adjuvant Hypofractionation Radiotherapy for Thymic Epithelial Tumours After Complete Resection
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| 1 years, 2 years, 5 years |
| local recurrence | recurrence of tumor bed | 2 years, 5 years |
| Intrathoracic recurrence / pleural metastasis | Rate of Intrathoracic recurrence / pleural metastasis | 2 years, 5 years |
| metastasis free survival | From the date of resection to the date of metastasis or death | 2 years, 5 years |
| D006425 |
| Hemic and Lymphatic Diseases |