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| Name | Class |
|---|---|
| Shandong University of Traditional Chinese Medicine | OTHER |
| The Second Hospital of Shandong University | OTHER |
| The Affiliated Hospital of Qingdao University | OTHER |
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This is a large observational cohort study to assess the impact of COVID-19 infection on pregnancy outcomes and offspring health.
The influence of SARS-CoV-2 infection on reproductive outcomes has been uncertain. The goal of this observational study is to assess the impact of COVID-19 infection on pregnancy outcomes and offspring health for patients with childbearing needs.
Participants will:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| COVID-19 group | Patients infected by SARS CoV2 before reproductive events. |
| |
| Control group | Patients who were not infected by SARS CoV2 before reproductive events. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| No intervention | Other | Participants are not subjected to any specific intervention. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Clinical pregnancy rate | Clinical pregnancy is defined as the ultrasound confirmation of at least one gestational sac. | 7 weeks after the day of embryo transfer |
| Ongoing pregnancy rate | Ongoing pregnancy is defined as continued pregnancy beyond 12 weeks of gestation. | 12 weeks after the day of embryo transfer |
| Measure | Description | Time Frame |
|---|---|---|
| Live birth rate | Live birth is defined as the delivery of any neonate with signs of life at ≥ 28 weeks of gestation. | 10 months after the day of embryo transfer |
| Pregnancy loss rate | Pregnancy loss is defined as pregnancy that eventuates in a spontaneous abortion or therapeutic abortion that occurred throughout pregnancy. |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with reproductive needs are recruited for study.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Zi-Jiang Chen | Contact | +0086 531 85187856 | chenzijiang@hotmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Zi-Jiang Chen | Shandong University | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Institute of Women, Children and Reproductive Health | Recruiting | Jinan | Shandong | 250012 | China |
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| ID | Term |
|---|---|
| D000086382 | COVID-19 |
| ID | Term |
|---|---|
| D011024 | Pneumonia, Viral |
| D011014 | Pneumonia |
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
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| Yantai Yuhuangding Hospital |
| OTHER |
| Yantai City Yantai Mountain Hospital | UNKNOWN |
| Jining First People's Hospital | OTHER |
| Weifang People's Hospital | OTHER |
| Affiliated Hospital of Jining Medical University | OTHER |
| Linyi People's Hospital | OTHER |
| Dezhou People's Hospital | OTHER |
| The Affiliated Hospital of Binzhou Medical College | UNKNOWN |
| Liaocheng People's Hospital | OTHER |
| The Second People's Hospital of Liaocheng | UNKNOWN |
| Linyi Maternal and Child Healthcare Hospital | UNKNOWN |
| Heze Hospital of Traditional Chinese Medicine | UNKNOWN |
| Weihai maternal and child health care hospital | UNKNOWN |
| Weifang Maternal and Child Health Hospital | UNKNOWN |
| Taian City Central Hospital | OTHER |
| Zibo Maternal and Child Health Hospital | OTHER |
| Qingdao Women and Children's Hospital | UNKNOWN |
| Affiliated Hospital of Shandong University of Traditional Chinese Medicine | OTHER |
| Qilu Hospital of Shandong University | OTHER |
| The Affiliated Hospital of Weifang Medical College | UNKNOWN |
| Maternal and Child Health Care Hospital of Shandong Province | UNKNOWN |
| Ren Ji Hospital of Shanghai Jiao Tong University | UNKNOWN |
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| 10 months after the day of embryo transfer |
| Congenital malformation rate | The number of the malformation neonates/the number of the neonates alive ×100%. | 12 months after the day of embryo transfer |
| D014777 |
| Virus Diseases |
| D018352 | Coronavirus Infections |
| D003333 | Coronaviridae Infections |
| D030341 | Nidovirales Infections |
| D012327 | RNA Virus Infections |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |