Prostate Diffusion Imaging With Distortion Correction

Prostate Diffusion Imaging With Distortion Correction

There has been literature demonstrating the effectiveness of correcting these MRI images by using an additional measurement of the magnetic field, but the implied improvement in lesion detection in these common distorted regions in the prostate has yet to be shown.

We propose that introducing this distortion correction would greatly improve the DWI images used for tumour detection. For this study we propose testing this hypothesis as a primary objective, and as a secondary objective including additional b-values to further refine the ADC value. The study involves adding one additional distortion correcting scan to the standard clinical study, adding approximately 2 minutes to the study.

Inclusion Criteria:

• Male
• Aged 18 and over
• No contraindication to MR scanning
• Smokers and non-smokers
• Patients who have had a complete scan on the 3T scan MRI at Norfolk and Norwich University Hospital and have gone on to have a biopsy at the Norfolk and Norwich University Hospital

Exclusion Criteria:

• Previous diagnosis of prostate cancer, prostatic biopsy or treatment for prostate cancer