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This prospective randomized study investigated the reproducibility of breast shape, radiation dose irradiated to the lungs, heart, dose distribution, patient satisfaction, and treatment toxicity when wearing and not wearing a bra during radiotherapy for patients with breast cancer.
Post-surgery radiotherapy to the breast is standard treatment after breast-conserving surgery in patients with breast cancer. In order to apply the latest radiation therapy technologies, such as intensity-modulated radiotherapy, it is important to maintain the correct posture. However, due to the nature of the breast made of soft tissue, it is difficult to maintain the same breast shape during each treatment. This is especially difficult for large, ptotic breasts. Accordingly, we developed a bra for breast cancer patients in order to perform accurate radiotherapy. It was designed to fix the breast using bands in various directions so that its shape and position can be fixed during radiation treatment.
This is a prospective, randomized controlled study to evaluate the effects of using a bra for breast cancer patients on the reproducibility of breast shape, radiation dose irradiated to the lungs, heart, dose distribution, patient satisfaction, and treatment toxicity.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group wearing a bra | Experimental | Patients wear a bra while receiving radiotherapy. |
|
| Group not wearing a bra | No Intervention | Patients do not wear a bra while receiving radiotherapy. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Group wearing a radiotherapy bra | Device | Group wearing a radiotherapy bra |
|
| Measure | Description | Time Frame |
|---|---|---|
| The reproducibility of breast shape through cross-correlation values, both with and without the use of a bra | Evaluating the reproducibility of breast shape through cross-correlation values in cone-beam CT and planning CT matching. This study involves comparing groups of patients wearing and not wearing a bra | During the radiotherapy, an average of 1 month |
| Measure | Description | Time Frame |
|---|---|---|
| Radiation dosimetric evaluation | radiation dose to lungs, heart and breast | at the time of completion of radiotherapy |
| Patient satisfaction assessment |
|
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Inclusion Criteria:
Exclusion Criteria:
breast cancer
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| Name | Affiliation | Role |
|---|---|---|
| Hwakyung BYUN, professor | Severance Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Yongin Severance Hospital | Yongin-si | 365 | South Korea |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 39952437 | Derived | Byun HK, Kim H, Son J, Cho Y, Kwon YJ, Kim DW, Lee H, Kim YB. Impact of bra application in breast cancer radiotherapy: A pilot prospective randomized trial. Radiother Oncol. 2025 May;206:110785. doi: 10.1016/j.radonc.2025.110785. Epub 2025 Feb 12. |
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| ID | Term |
|---|---|
| D001943 | Breast Neoplasms |
| ID | Term |
|---|---|
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D001941 | Breast Diseases |
| D012871 | Skin Diseases |
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Test group: Group wearing a radiotherapy bra / Control group: Group not wearing a radiotherapy bra -Allocation: Random -Blinding: None -Time: Prospective
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Test group: Group wearing a radiotherapy bra / Control group: Group not wearing a radiotherapy bra -Allocation: Random -Blinding: None -Time: Prospective
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| at the time of completion of radiotherapy |
| Assessment of treatment toxicity |
| at 6 months and 12 months after the radiotherapy |
| D017437 |
| Skin and Connective Tissue Diseases |