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Maternal infectious morbidity is a common complication of cesarean delivery, especially in a poor recourse setting like ours. This study was done to compare the effectiveness of preoperative vaginal cleansing with immediate postoperative vaginal cleansing with chlorhexidine solution in preventing post-cesarean infectious morbidities. Randomized trial involving 120 consented women who had elective or emergency cesarean sections at term, 60 in each group. Group 1 had preoperative while group 2 had postoperative vaginal cleansing with 1% chlorhexidine.
Background: Maternal infectious morbidity is a common complication of cesarean delivery, especially in a poor recourse setting like ours. This study was done in a tertiary hospital in Abakaliki, Ebonyi State, Southeast Nigeria over a period of 5 months. The State is inhabited mainly by rural farmers and petty traders. Literacy is low and poverty is common with poor maternal health indices.
Aim: To compare the effectiveness of preoperative vaginal cleansing with immediate postoperative vaginal cleansing with chlorhexidine solution in preventing post-cesarean infectious morbidities.
Method: Randomized trial involving 120 consented women who had elective or emergency cesarean sections at term, 60 in each group. Group 1 had preoperative while group 2 had postoperative vaginal cleansing with 1% chlorhexidine. Research Randomizer software was used to generate 120 numbers. Sixty numbers were randomly generated from a pool of 120 numbers and were assigned to group 1 while the remaining 60 numbers were automatically assigned to group 2. Both groups received antibiotics and anterior abdominal wall scrubbing. There were monitored for symptoms and signs of endometritis, wound infection and pyrexia till discharge.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| First arm - Pre-operative vaginal cleansing with chlorhexidine | Active Comparator | Had vaginal cleansing with chlorhexidine prior to cesarean section and were monitored for infectious morbidity. |
|
| Second arm - Post-operative vaginal cleansing with chlorhexidine | Active Comparator | Had vaginal cleansing with chlorhexidine after cesarean section and were monitored for infectious morbidity. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Chlorhexidine | Procedure | Pre-operative and post-operative vaginal cleansing. |
|
| Measure | Description | Time Frame |
|---|---|---|
| infectious morbidity | development of infectious morbidity following cesarean section after vaginal cleansing. | six (6) weeks. |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Alex Ekwueme Federal University Teaching Hospital | Abakaliki | Ebonyi State | 480001 | Nigeria |
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| ID | Term |
|---|---|
| D002710 | Chlorhexidine |
| D019072 | Antibiotic Prophylaxis |
| ID | Term |
|---|---|
| D001645 | Biguanides |
| D006146 | Guanidines |
| D000578 | Amidines |
| D009930 | Organic Chemicals |
| D018890 |
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|
| Chemoprevention |
| D004358 | Drug Therapy |
| D013812 | Therapeutics |
| D011292 | Premedication |