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To validate and investigate the efficacy of comprehensive functional assessments for the diagnostic and prognostic value in NOCAD.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| NCF cohort | Normanl coronary-flow patients referred to coronary angiography and undergo assessment with single photon emission computed tomography imaging (SPECT). |
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| CSF cohort | Coronary slow-flow patients referred to coronary angiography and undergo assessment with single photon emission computed tomography imaging (SPECT). |
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| ANOCA cohort | Angina with nonobstructive coronary artery patients referred to coronary angiography and undergo assessment with single photon emission computed tomography imaging (SPECT). |
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| INOCA cohort | Ischemia with nonobstructive coronary artery patients referred to coronary angiography and undergo assessment with single photon emission computed tomography imaging (SPECT). |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| coronary physiological indices | Device | coronary physiological indices |
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| Measure | Description | Time Frame |
|---|---|---|
| Major adverse cardiac events (MACE) | The composite of coronary heart disease death, nonfatal myocardial infarction, hospitalization for unstable angina, or fatal or nonfatal ischemic stroke. | 5 years |
| Measure | Description | Time Frame |
|---|---|---|
| Individual components of MACE | Cumulative incidence of the individual components of MACE | 5 years |
| the change in Seattle Angina Questionnaire (SAQ) summary score | The SAQ comprises 5 components namely physical limitation, angina stability, angina frequency, treatment satisfaction, and quality of life; these are then incorporated into the summary score. The higher the score, the better the patient's quality of life and physical function. |
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Inclusion Criteria:
Exclusion Criteria:
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The study population enrolled from Zhongshan Hospital, Fudan University (Shanghai, China)，with coronary angiography and available cadmium zinc telluride - single photon emission computed tomography imaging (CZT-SPECT).
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| Name | Affiliation | Role |
|---|---|---|
| Chenguang Li | Fudan University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Zhongshan hospital, Fudan university | Shanghai | China |
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| ID | Term |
|---|---|
| D003324 | Coronary Artery Disease |
| D017202 | Myocardial Ischemia |
| ID | Term |
|---|---|
| D003327 | Coronary Disease |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D001161 | Arteriosclerosis |
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| 5 years |
| the change in Seattle Angina Questionnaire (SAQ) score of indivadual scale | The SAQ comprises 5 components namely physical limitation, angina stability, angina frequency, treatment satisfaction, and quality of life. The higher the score, the better the patient's quality of life or physical function. | 5 years |
| D001157 |
| Arterial Occlusive Diseases |
| D014652 | Vascular Diseases |