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This study aims to determine whether microneedling or dermabrasion in the early post-operative period is superior in improving the appearance of surgical scars on the face.
Microneedling and dermabrasion are two common modalities that may be performed in-office to treat surgical scars.
Microneedling is a form of collagen induction therapy, often used in conjunction with platelet-rich plasma or hyaluronic acid.
Dermabrasion is a technique that improves the skin structure, quality, and appearance of scars through collagen remodeling and reepithelization.
To determine which modality is most effective, a prospective study; randomizing a volunteer sample of adult patients with new surgical vertical forehead scars will receive either dermabrasion or microneedling in the early postoperative period.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| microneedling | Active Comparator | microneedling is a form of collagen induction therapy, often used in conjunction with platelet-rich plasma or hyaluronic acid - Patients will receive two treatments, once at 6-8 weeks following facial surgery, and the second at 12-16 weeks following facial surgery |
|
| dermabrasion | Active Comparator | dermabrasion is a technique that improves the skin structure, quality, and appearance of scars through collagen remodeling and reepithelization - Patients will receive the standard of care treatment 6-10 weeks following facial surgery |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Microneedling | Procedure | a form of collagen induction therapy |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Change in Vancouver Scar Scale Scores | Four characteristics of the scar are assessed. These are: vascularity, height, pliability, and pigmentation. Each characteristic is given a score, which are added together to give an overall score between 0 and 13 - lower scores denoting normal skin | Month 7 |
| Change in Patient and Observer Scar Assessment Scale Scores | Items and total scale scores for the patient and observer: Each item on both scales has a score of 1 to 10. The lowest score is 1 and corresponds to the normal skin situation. The total score of both scales can be calculated simply by adding the scores of each of the six items. The total score will range from 6 to 60 - lower scores denoting normal skin | Month 7 |
| Change in Global Aesthetic Improvement Scale Scores | 5-point scale wherein 2 = much improved (marked improvement in appearance), 1 = improved (improvement in appearance but a touch-up or re-treatment is indicated - lower scores denoting normal skin | Month 7 |
| Measure | Description | Time Frame |
|---|---|---|
| Patient perceived benefit | At the time of intervention, patients will be asked to rank pain of procedure on a scale of 1-10 (1: minimal discomfort, 10: severe pain). At 6 months, they will also give a yes/no response as to whether they would undergo the study protocol (procedure) again. | At time of procedure (pain scale); at 6 months (yes/no) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Candace M Waters, MD | Contact | 336-716-4000 | cmwaters@wakehealth.edu | |
| Alexa l Lacy | Contact | 336-716-3850 | Alexa.Lacy@advocatehealth.org |
| Name | Affiliation | Role |
|---|---|---|
| Candace M Water, MD | Wake Forest University Health Sciences | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Wake Forest University Health Sciences | Recruiting | Winston-Salem | North Carolina | 27157 | United States |
photo documentation, de-identified, for review of scar appearance after treatment
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Data will become available after all data collection is complete in order to perform independent blinded analysis of scars at all time points.
Researchers on the study protocol involved in scar assessment
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| ID | Term |
|---|---|
| D002921 | Cicatrix |
| ID | Term |
|---|---|
| D005355 | Fibrosis |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D000097244 | Percutaneous Collagen Induction |
| D003869 | Dermabrasion |
| ID | Term |
|---|---|
| D000529 | Complementary Therapies |
| D013812 | Therapeutics |
| D026741 | Physical Therapy Modalities |
| D011677 | Punctures |
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Patients will be invited to participate in the study through the clinic setting - aim to have around 30 patient volunteers. Of the 30 patients, 15 will be randomized to receive microneedling, and 15 will receive dermabrasion.
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| Dermabrasion |
| Procedure |
a technique that improves the skin structure, quality, and appearance of scars through collagen remodeling and reepithelization |
|
| D012046 |
| Rehabilitation |
| D003357 | Cosmetic Techniques |
| D062109 | Dermatologic Surgical Procedures |
| D019651 | Plastic Surgery Procedures |
| D013514 | Surgical Procedures, Operative |