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| Name | Class |
|---|---|
| University of Maryland | OTHER |
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The goal of this observational study is to investigate the potential differences in thrombogenicity between black and white patients admitted with atherothrombotic events including acute coronary syndrome, multi-vessel coronary disease, and ischemic stroke.
Participants will engage in laboratory testing and health outcome assessments.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patient | (Secondary Prevention) Includes black (n=150) and white (n=150) patients greater than or equal to 18 years of age hospitalized for acute coronary syndrome (ACS), multi-vessel disease, or ischemic stroke undergoing intervention |
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| Family Member | (Primary Prevention) Includes black subjects (n=75) who are first or second-degree relatives of patients in Cohort 1 and have no history of prior hospitalization for cardiovascular or cerebrovascular disease |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Life and Medication Recommendations | Behavioral | Based on obtained subjective and objective data from patient-filled questionnaire and laboratory testing respectively, lifestyle and medication recommendations will be provided for secondary prevention of cardiovascular and cerebrovascular diseases |
| Measure | Description | Time Frame |
|---|---|---|
| Differences in Platelet Fibrin Clot Formation (MA,mm) | Differences in Platelet Fibrin Clot Formation (MA,mm) Between Black and White Patients | Baseline |
| Differences in Speed of Clot Formation (R, min) | Differences in Speed of Clot Formation (R, min) Between Black and White Patients | Baseline |
| Measure | Description | Time Frame |
|---|---|---|
| Major Adverse Cardiovascular Events Post Index Hospitalization | Major Adverse Cardiovascular Events (death, MI, stroke, unplanned target vessel revascularization, major bleeding) Post Index Hospitalization | 3 and 12 months post index hospitalization |
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Inclusion Criteria:
Exclusion Criteria:
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Two Cohorts (Cohort 1 = Secondary Prevention, Cohort 2 = Primary Prevention)
- See information about specific Cohorts
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Kevin Bliden, BS, MBA | Contact | 4432441497 | kbliden@lifebridgehealth.org |
| Name | Affiliation | Role |
|---|---|---|
| Jenna Brager, PhD | LifeBridge Health | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Sinai Hospital of Baltimore | Recruiting | Baltimore | Maryland | 21215 | United States |
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| ID | Term |
|---|---|
| D054058 | Acute Coronary Syndrome |
| D000083242 | Ischemic Stroke |
| ID | Term |
|---|---|
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D014652 | Vascular Diseases |
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| D020521 |
| Stroke |
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |