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Blood pressure will be measured in min. 5/10/15 after birth. Cerebral tissue oxygenation (crSO2) monitoring with NIRS in addition to routine arterial oxygen saturation (SpO2) monitoring with pulse oximetry will be performed continuously during the first 15 minutes after birth
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Term neonates | Neonates with gestational age 37+0 - 42+0 weeks |
| |
| Preterm neonates | Neonates with gestational age < 37+0 weeks |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cerebral tissue oxygenation and blood pressure measurement | Diagnostic Test | Measurement of cerebral tissue oxygenation with NIRS and blood pressure during immediate transition after birth |
| Measure | Description | Time Frame |
|---|---|---|
| Blood pressure | Systolic, diastolic and mean blood pressure in mmHg measured with a pneumatic cuff | 5, 10 and 15 minutes after birth |
| Cerebral oxygenation | Cerebral tissue oxygen saturation in percent measured with NIRS | 5, 10 and 15 minutes after birth |
| Measure | Description | Time Frame |
|---|---|---|
| Cardiac output | Calculated out of blood pressure and heart rate | 5, 10 and 15 minutes after birth |
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Inclusion Criteria:
Term and preterm neonates observed routinely immediately after birth at the resuscitation desk
Exclusion Criteria:
No decision to conduct full life support
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Term and preterm neonates observed routinely at the resuscitation desk at the Division of Neonatology, Department of Pediatrics, Medical University of Graz will be eligible for the study.
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| Name | Affiliation | Role |
|---|---|---|
| Gerhard Pichler, Prof | Medical University of Graz | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| medical university of Graz | Graz | 8010 | Austria |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24481411 | Background | Pichler G, Cheung PY, Aziz K, Urlesberger B, Schmolzer GM. How to monitor the brain during immediate neonatal transition and resuscitation? A systematic qualitative review of the literature. Neonatology. 2014;105(3):205-10. doi: 10.1159/000357162. Epub 2014 Jan 25. | |
| 25671807 | Background | Hooper SB, Te Pas AB, Lang J, van Vonderen JJ, Roehr CC, Kluckow M, Gill AW, Wallace EM, Polglase GR. Cardiovascular transition at birth: a physiological sequence. Pediatr Res. 2015 May;77(5):608-14. doi: 10.1038/pr.2015.21. Epub 2015 Feb 4. |
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| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| Prot_SAP | Yes | Yes | No | Study Protocol and Statistical Analysis Plan | May 5, 2022 | Dec 4, 2023 | Prot_SAP_000.pdf |
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| ID | Term |
|---|---|
| D001795 | Blood Pressure Determination |
| ID | Term |
|---|---|
| D003935 | Diagnostic Techniques, Cardiovascular |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
| D010808 | Physical Examination |
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| 28427056 | Background | Baik N, Urlesberger B, Schwaberger B, Avian A, Mileder L, Schmolzer GM, Pichler G. Blood Pressure during the Immediate Neonatal Transition: Is the Mean Arterial Blood Pressure Relevant for the Cerebral Regional Oxygenation? Neonatology. 2017;112(2):97-102. doi: 10.1159/000455965. Epub 2017 Apr 21. |