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Craniofacial fibrous dysplasia (CFD) is a nonneoplastic disease characterized by fibro-osseous lesions in the affected bones. Treatment is mainly surgical and is stratified based on four different anatomical zones. This study aimed to evaluate the long-term outcomes and refine the algorithm for CFD.
According to Chen et. al for the appropriate surgical management of FD the craniofacial skeleton can be divided into four zones according to the consideration of facial cosmesis, vital anatomical region and function preserving. The aim of the study was to evaluate the outcome of nearly 40 years long-term follow up cohort group and refine the algorithm of surgical intervention of FD under 4 zones classification.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Craniofacial fibrous dysplasia | Fibro-osseous lesions within the affected bones based on image, and surgical intervention based on 4 different anatomical zones. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Craniofacial reconstruction | Procedure | Zone 1 lesions: radical excision and immediate reconstruction with bone grafts for fibrous dysplasia lesions. Zone 2 lesions: trimming & recontouring. Zone 3 lesions: observation or conservative recontouring; optic nerve decompression performed when continuous deterioration of vision, and external auditory canal surgery performed when cholesteatoma/near total ear canal stenosis. Zone 4: observation or conservative recontouring; orthognathic surgery performed when malocclusion or midface retrusion noted. |
| Measure | Description | Time Frame |
|---|---|---|
| Recurrence | Recurrence based on facial bone computed tomography | Personal interviews with facial bone computed tomography obtained on late 2019 and 2020 |
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Inclusion Criteria:
Exclusion Criteria:
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Patient with craniofacial fibrous dysplasia, and received craniofacial surgery
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| Name | Affiliation | Role |
|---|---|---|
| Pang-Yun Chou | Chang Gung Memorial Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Chang Gung Memorial Hospital | Taoyuan | Taiwan |
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| ID | Term |
|---|---|
| D000077275 | Craniofacial Fibrous Dysplasia |
| ID | Term |
|---|---|
| D005357 | Fibrous Dysplasia of Bone |
| D010009 | Osteochondrodysplasias |
| D001848 | Bone Diseases, Developmental |
| D001847 | Bone Diseases |
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| D009140 | Musculoskeletal Diseases |