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Since the emergence of Corona Virus Disease 2019(COVID-19), it has spread rapidly around the world, And it has had a profound impact on the lives and health of people around the world, most of the COVID-19 positive patients are 3-4 weeks after the onset of infection patients can turn negative and recover, however, increasing observational data suggest that these patients long-term or recurring symptoms such as: fatigue, palpitations, cognitive impairment, dyspnea, anxiety, chest tightness and Pain, etc., symptoms may last at least two months or even longer (for example, up to 12 months), the patient's quality of life and The ability to work and social activities also decline accordingly. Therefore, in addition to the acute symptoms after infection, patients also face the same. The challenge of long-term health sequelae associated with COVID-19.
Relevant studies have shown that breathing training can improve the exercise capacity, lung function, and respiratory rate of patients who have recovered from COVID-19. Difficult and other aspects are safe and effective. However, because COVID-19 is an emerging disease, the clinical research literature so far has limited Clinical data are still insufficient, and the effect of respiratory training on the breathing and physical function of COVID-19 patients has not been determined, and most of the patients are not living in the hospital. How to carry out simple and effective breathing training to reduce the long-term impact of COVID-19 on patients is worthy of continuous discussion. This study will assist COVID-19 patients to perform respiratory training with incentive spirometer intervention, and collect patients before and after the intervention Oxygen requirements, blood draw values and Post-COVID-19 Functional Status scale(PCFS scale) and other data to explore and evaluate the effect of interventional breathing training on the improvement of symptoms of new coronary pneumonia, as a reference for future clinical treatment and improvement of symptoms of COVID-19.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Experimental | No Intervention | Patients who have recovered from COVID-19 | |
| Three months after recovering from COVID-19 | Experimental | Patients who have from COVID-19 in three months |
|
| Six months after recovering from COVID-19 | Experimental | Patients who have from COVID-19 in three to six months |
|
| Nine months after recovering from COVID-19 | Experimental | Patients who have from COVID-19 in six to nine months |
|
| Twelve months after recovering from COVID-19 | Experimental | Patients who have from COVID-19 in nine to twelve months |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| breathing training | Device | Breathing training for six weeks. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Oxygen requirements, blood draw values | Oxygen requirements, blood draw values | 6 WEEKS |
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Inclusion Criteria:
1. Patients who have recovered from COVID-19
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Yao-Hsiang Chen | Tri Service General Hospital Sonshan Branch | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Tri Service General Hospital Sonshan Branch | Taipei | 105309 | Taiwan |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 42330008 | Derived | Chen YH, Lin CH, Liu JH, Lin HA, Hsieh YS. Effects of incentive spirometer training on dyspnea and functional status in patients with long COVID. PLoS One. 2026 Jun 22;21(6):e0351553. doi: 10.1371/journal.pone.0351553. eCollection 2026. |
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| ID | Term |
|---|---|
| D000086382 | COVID-19 |
| D000094024 | Post-Acute COVID-19 Syndrome |
| D004417 | Dyspnea |
| ID | Term |
|---|---|
| D011024 | Pneumonia, Viral |
| D011014 | Pneumonia |
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
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| ID | Term |
|---|---|
| D001945 | Breathing Exercises |
| ID | Term |
|---|---|
| D026441 | Mind-Body Therapies |
| D000529 | Complementary Therapies |
| D013812 | Therapeutics |
| D026241 | Exercise Movement Techniques |
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|
| D014777 |
| Virus Diseases |
| D018352 | Coronavirus Infections |
| D003333 | Coronaviridae Infections |
| D030341 | Nidovirales Infections |
| D012327 | RNA Virus Infections |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D000094025 | Post-Infectious Disorders |
| D002908 | Chronic Disease |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D012120 | Respiration Disorders |
| D012818 | Signs and Symptoms, Respiratory |
| D012816 | Signs and Symptoms |
| D026741 |
| Physical Therapy Modalities |