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Data comparing prilocaine vs bupivacaine in equipotent doses in the elderly are lacking; therefore, the study will compare the effect of prilocaine vs bupivacaine on hemodynamics in spinal anesthesia for geriatric patients undergoing endoscopic urological surgeries
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Prilocaine group | Active Comparator |
| |
| Bupivacaine GROUP | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Prilocaine | Drug | The patients will receive a single injection of spinal anesthesia using prilocaine plus fentanyl |
|
| Measure | Description | Time Frame |
|---|---|---|
| Hypotension | Incidence of hypotension from local anesthetic injection | Till 30 minutes after spinal anesthesia. |
| Measure | Description | Time Frame |
|---|---|---|
| Use of vasopressor drugs | Total doses of vasopressor drugs used for hypotension treatment | Until the patient will have no lower limbs motor weakness assessed up to 6 hours after spinal anesthesia |
| Measure | Description | Time Frame |
|---|---|---|
| Mean and systolic arterial blood pressure values | Mean and systolic arterial blood pressure values after spinal anesthesia | Until the patient will have no lower limbs motor weakness assessed up to 6 hours after spinal anesthesia |
| Heart rate |
Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Kasr Alaini hospital | Cairo | Egypt |
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| ID | Term |
|---|---|
| D011318 | Prilocaine |
| D002045 | Bupivacaine |
| ID | Term |
|---|---|
| D000813 | Anilides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D000814 | Aniline Compounds |
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| Bupivacaine | Drug | The patients will receive a single injection of spinal anesthesia using Bupivacaine plus fentanyl |
|
Heart rate after spinal anesthesia
| Until the patient will have no lower limbs motor weakness assessed up to 6 hours after spinal anesthesia |
| D000588 |
| Amines |