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The purpose of this study is to determine the effects of added probiotic cultures to a carbohydrate + protein recovery beverage compared to a similar recovery beverage without probiotic cultures, in its ability to impact endurance performance, perceived ratings of gastrointestinal symptoms and markers of inflammation and intestinal damage.
In a randomized, crossover fashion, the investigators will assess changes in exercise performance, gastrointestinal symptom rating scale scores, as well as interleukin-6 and intestinal fatty-acid binding protein levels following consumption of either water, kefir or flavored milk.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Water | Placebo Comparator | Water |
|
| Flavored Kefir | Experimental | 1% Lowfat Kefir manufactured by Lifeway Kefir and containing 18 g of CHO, 10 g of protein, and 2 g of fat |
|
| Flavored Milk | Active Comparator | 1% Lowfat Milk manufactured by Prairie Farms and containing 24 g of CHO, 8 g of protein, and 2.5 g of fat |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Water | Other | 340 mL plain tap water consumed immediately following glycogen depleting exercise |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Aerobic Performance Times | 5 kilometer running time-trial on a curved, non-motorized treadmill | Through study completion, an average of 3 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Blood Interleukin-6 | Blood interleukin-6 concentrations in response to intense exercise | Through study completion, an average of 3 weeks |
| Blood Intestinal fatty-acid binding protein | Blood Intestinal fatty-acid binding protein concentrations in response to intense exercise |
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Inclusion Criteria:
Exclusion Criteria:
Alcohol consumption (more than 2 standard alcoholic drinks per day or more than 10 drinks per week) or drug abuse or dependence.
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| Name | Affiliation | Role |
|---|---|---|
| Chad M Kerksick, PhD | Lindenwood University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Exercise and Performance Nutrition Laboratory | Saint Charles | Missouri | 63301 | United States |
The investigators do not plan to make IPD available to other researchers
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| ID | Term |
|---|---|
| D014867 | Water |
| ID | Term |
|---|---|
| D006878 | Hydroxides |
| D000468 | Alkalies |
| D007287 | Inorganic Chemicals |
| D000838 | Anions |
| D007477 |
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Randomized, crossover.
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Both participant and investigator are unmasked to treatment conditions
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| Flavored Kefir |
| Other |
320 mL kefir consumed immediately following glycogen depleting exercise |
|
| Flavored Milk | Other | 240 mL flavored milk consumed immediately following glycogen depleting exercise |
|
| Through study completion, an average of 3 weeks |
| Gastrointestinal Symptoms | Gastrointestinal Symptoms measured using the Gastrointestinal Symptoms Rating Scale (GSRS) in response to intense exercise. The scale asks 15 questions, and asks participants to rate their gastrointestinal symptoms on a 7 point scale with 0 being no discomfort at all and 7 being very severe discomfort. Lower total GSRS scores indicate a better outcome. | Through study completion, an average of 3 weeks |
| Ions |
| D004573 | Electrolytes |
| D010087 | Oxides |
| D017601 | Oxygen Compounds |