The Incidence of Hypocalcemia in Pregnant Women at Siriraj Hospital

The Incidence of Hypocalcemia in Pregnant Women at Siriraj Hospital

Calcium is an essential element for fundamental physiological functions and during pregnancy. However, higher calcium intake can induce constipation, flatulence, nausea, or kidney stones. This study aims to evaluate the incidence of hypocalcemia among pregnant women in the first half of pregnancy in Thailand. Also, Comparison of calcium level in pregnant women in the third trimester who received and not received calcium during pregnancy.

The primary outcome is the incidence of hypocalcemia among pregnant women in the first half of pregnancy. This study also has secondary objectives. The one is associating factors with calcium level. After getting the results of maternal calcium level, the normal calcium level group will be divided into 2 groups for receiving calcium 1 g/day and no receiving calcium supplement. Another with hypocalcemia group will be decided into 2 groups for receiving calcium 1 g/day and 2 g/day. The calcium level was collected again in the third trimester.

Inclusion Criteria:

• Pregnant women who attend antenatal care clinic in Siriraj Hospital
• Pregnant women with gestation less than 20 weeks of gestation
• Singleton pregnancy

Exclusion Criteria:

• Pregnant women who has underlying diseases including liver disease and vitamin D deficiency
• Pregnant women are malnutrition patients
• Pregnant women who receive calcium supplement before enrollment