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The aim of our study is to evaluate the prognostic roles of serum albumin level and systemic inflammation-related indices, including and not including serum albumin level, in the radiological progression of gonarthrosis. In this retrospective study, between 10.01.2017 and 10.01.2022, the data of the patients between the ages of 50-80, who applied to Ufuk University Physical Medicine and Rehabilitation clinic with the complaint of knee pain and met the clinical criteria of the American Rheumatology Association for gonarthrosis (knee osteoarthritis) (knee pain on many days of the previous month, crepitation with active joint movement, morning stiffness lasting ≤ 30 minutes, age ≥38 years, bone enlargement of the knee on examination),and whose knee radiography and blood tests were evaluated at admission were scanned.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| serum albumin level | Other | serum albumin level in gonarthrosis |
| Measure | Description | Time Frame |
|---|---|---|
| serum albumin level | serum albumin level | 1 month |
| The Aggregate Index of Systemic Inflammation (AISI) | Neutrophil countxPlatelet countxMonocyte count/ Lymphocyte count | 1 month |
| Systemic Inflammatory Response Index (SIRI) | Neutrophil countxMonocyte count/ Lymphocyte count | 1 month |
| Systemic Immune Inflammation Index (SII) | Platelet countxNeutrophil count/Lymphocyte count | 1 month |
| Prognostic Nutrisyonel Index (PNI) | Serum albumin concentration (g/l) + (5xlymphocyte count (thousand/microlitre) | 1 month |
| Modified Systemic Inflammation Score (mSIS) | Serum albumin concentration <40g/l ve LMR<3.4: score 2 Serum albumin concentration ≥40 g/l veya LMR≥3.4: score 1 Serum albumin concentration ≥40 g/l ve LMR≥3.4: score 0 | 1 month |
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Inclusion Criteria:
Exclusion Criteria:
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- In this retrospective study, between 10.01.2017 and 10.01.2022, the data of the patients between the ages of 50-80, who applied to Ufuk University Physical Medicine and Rehabilitation clinic with the complaint of knee pain and met the clinical criteria of the American Rheumatology Association for gonarthrosis and whose knee radiography and blood tests were evaluated at admission were scanned. In order to compare the parameters to be included in the study, the data and blood tests of patients between the ages of 50-80 who applied to Ufuk University Physical Medicine and Rehabilitation clinic between 10.01.2017 and 10.01.2022 for reasons other than knee pain were scanned.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ufuk University | Ankara | Çankaya | 06520 | Turkey (Türkiye) |
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| ID | Term |
|---|---|
| D020370 | Osteoarthritis, Knee |
| D034141 | Hypoalbuminemia |
| ID | Term |
|---|---|
| D010003 | Osteoarthritis |
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
| D012216 | Rheumatic Diseases |
| D007019 | Hypoproteinemia |
| D001796 | Blood Protein Disorders |
| D006402 | Hematologic Diseases |
| D006425 | Hemic and Lymphatic Diseases |
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| ID | Term |
|---|---|
| D012709 | Serum Albumin |
| ID | Term |
|---|---|
| D000418 | Albumins |
| D011506 | Proteins |
| D000602 | Amino Acids, Peptides, and Proteins |
| D001798 | Blood Proteins |
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