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This study focuses on the construction of a biological sample library for organoids and tumor tissues in gynecological tumors.
Explore the construction and maintenance of a large-scale queue of gynecological tumor organoids. Beijing Daxiang Technology Co., Ltd. provides corresponding technical support and chip design. Gynecological oncology center provides tumor samples, clinical information, and pathological support, and biological sample library provides technical support, storage space, and quality management.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| cohort of cervical cancer organoids | organoids derived from cervical cancer |
| |
| cohort of endometrial cancer organoids | organoids derived from endometrial cancer |
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| cohort of ovarian cancer organoids | organoids derived from ovarian cancer |
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| cohort of vulva cancer organoids | organoids derived from vulva cancer |
| |
| cohort of vaginal cancer organoids | organoids derived from vaginal cancer |
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| cohort of gestational trophoblastic tumor organoids | organoids derived from gestational trophoblastic tumor |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| construction of organoids from gynecological tumor | Other | organoids construction |
|
| Measure | Description | Time Frame |
|---|---|---|
| Construction of BioBank | BioBank including organoids banks, tissue banks, PDX banks, immune cell banks, and primary banks from other tissue sources | one year |
| Measure | Description | Time Frame |
|---|---|---|
| Drug sensitivity detection based on organoids banks | Exploring drug sensitivity detection in gynecological tumors based on organoid libraries | one year |
| Exploring the molecular mechanism based on organoids banks |
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Inclusion Criteria:
Exclusion Criteria:
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Those diagnosed with gynecological oncology, including cervical cancer, endometrial cancer, ovarian cancer, vulva cancer, vaginal cancer, and gestational trophoblastic tumor.
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Biospecimen obtained from patients diagnosed with gynecological cancer from the cancer site.
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Exploring the molecular mechanism of gynecological tumor pathogenesis based on organoid banks
| one year |