The objective of this prospective, international cohort is to incorporate the low stable pressure (using Airseal Insufflator) approach and its associated parameters into the early rehabilitation program after colorectal surgery so as to shorten hospitalization up to the ambulatory care and reduce postoperative pain and opioid consumption.

Laparoscopy is currently the gold standard for the vast majority of abdominal surgeries, and especially for colectomy for cancer or benign diseases. There are many data showing the benefits of the laparoscopic approach to colectomy in terms of morbidity, post-operative pain and analgesic consumption, length of hospital stay, cosmetic results, and improved patient satisfaction. In 2002, consensus European guidelines recommended insufflating at the lowest pressure that still provides sufficient exposure. Considering these results, low-pressure laparoscopy is one of the alternatives that have been developed to do away with the complications of the pneumoperitoneum while retaining its advantages.

However, other factors may influence the outcomes of the low-pressure pneumoperitoneum such as the use of humidification and warming gaz, robotic or microsurgical instrumentation, neuromuscular blockade, patient positioning, pre-stretching of the abdominal wall, ventilation-induced changes, and probably individual patient factors like obesity. These parameters could not be separately tested in randomized trial. We should consider all these parameters in a prospective international registry in order to optimize the benefit of low-pressure pneumoperitoneum in post-operative recovery.

Inclusion Criteria:

• Age ≥ 18 years old
• Colonic resection (right or left, subtotal or total) performed for benign or malignant pathology
• Rectal resection with or without stoma for benign or malignant pathology
• Laparoscopic or robotic procedure
• Surgery under low stable pressure pneumoperitoneum with AirSeal
• Patient who benefits by medicare system
• Oral agreement after reading information letter

Exclusion Criteria:

• Laparotomy procedure
• Associated resection (except appendectomy or liver biopsy)
• Transverse colectomy
• Emergency procedure
• Pelvic sepsis
• Pregnancy or breast feeding period
• Legal incapacity or physical, psychological social or geographical status interfering with the patient's ability to agree to participate in the study
• Persons deprived of liberty or under guardianship

This cohort study is a pilot study assessing the best operative association with stable low-pressure pneumoperitoneum in order to optimize postoperative outcomes after mini-invasive colorectal surgery. The use of robotic or microsurgical instrumentation, neuromuscular blockade, patient positioning, pre-stretching of the abdominal wall and ventilation-parameters could not be separately tested in randomized trial.

In this pilot study, we aim to include 300 patients with low stable pneumoperitoneum with Colorectal surgery.

All patient assessements will be done according to the sites standard of care.

There are no plans to share individual participant data (IPD) with other researchers