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Through the clinical observation of Qingcheng Pingxian Granules in the treatment of acute exacerbation of chronic obstructive pulmonary disease (phlegm-heat lung syndrome), (1) to evaluate the safety of Qingcheng Pingxian Granules in the acute exacerbation of chronic obstructive pulmonary disease; (2) to observe the clinical efficacy of Qingcheng Pingxian Granules in the treatment of acute exacerbation of chronic obstructive pulmonary disease, to provide an effective medication and solution for the treatment of acute exacerbation of chronic obstructive pulmonary disease, and to provide data for the development of the further application of Qingcheng Pingxian Granules.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| treatment group | Experimental | Qingkepingchuan Granules+Conventional basic therapy |
|
| control subjects | Other | Conventional basic therapy |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Qingkepingchuan Granules | Drug | Qingkepingchuan Granules,Take it three times a day with water after meals. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Chinese Medicine Symptoms Scale | Record changes in patients' TCM indicators。The scale includes cough, wheezing, shortness of breath, sputum volume, chest tightness, sputum colour, sputum quality, fever, thirst, irritability, constipation, tongue coating, and pulse. The first four items are rated 0-6, and the last nine items are rated 0-3, with higher ratings indicating poorer treatment outcomes. | Before the start of treatment, 1 week of treatment, 2 weeks of treatment, 1 month of follow-up |
| COPD assessment test | Record changes in the patient's condition | Before the start of treatment, 1 week of treatment, 2 weeks of treatment, 1 month of follow-up |
| breathlessness measurement using the modified British Medical Research Council | Record changes in the patient's condition | Before the start of treatment, 1 week of treatment, 2 weeks of treatment, 1 month of follow-up |
| Measure | Description | Time Frame |
|---|---|---|
| 6-minute walking test | Record changes in the patient's condition | Before the start of treatment, 2 weeks of treatment |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Beijing University of Chinese Medicine | Beijing | China |
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Qingkepingchuan Granules
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| conventional treatment | Other | Oxygen intake, selection of appropriate antibiotics based on lab results, and other treatments |
|
| ID | Term |
|---|---|
| D029424 | Pulmonary Disease, Chronic Obstructive |
| ID | Term |
|---|---|
| D008173 | Lung Diseases, Obstructive |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D002908 | Chronic Disease |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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