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The purpose of this study is to determine the effects of using silk pillowcases in mild to moderate non-cystic acne prone skin in comparison to cotton pillowcases.
The investigators will evaluate acne severity/ lesion count, trans-epidermal water loss, and sebum production in participants. There is an equal chance of being assigned a 100% silk pillowcase or 100% cotton pillowcase.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Silk Pillowcase | Experimental | 100% Mulberry Silk Pillowcase used every night |
|
| Cotton Pillowcase | Active Comparator | 100% Cotton Pillowcase used every night |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Silk Pillowcase | Other | 100% Mulberry Silk Pillowcase |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Acne Lesion Counts: Inflammatory Lesions | The inflammatory lesion counts will be counted and compared against baseline | 8 weeks |
| Acne Lesion Counts: Non-Inflammatory Lesions | The non-inflammatory lesion counts will be counted and compared against baseline | 8 weeks |
| Facial Erythema Intensity Score | Facial erythema will be measured as the erythema intensity score as measured by the image analysis system (BTBP 3D Pro) | 8 Weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Transepidermal water loss | Change in Facial Trans-epidermal Water Loss, measured with vapometer | 8 Weeks |
| Sebum Excretion Rate | Shift in the facial sebum excretion rate, measured with sebumeter |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ajay S Dulai, MBBS MSc | Contact | 9167502463 | ajay@integrativeskinresearch.com | |
| Raja K Sivamani, MD MS AP | Contact | 9167502463 | raja.sivamani@integrativeskinresearch.com |
| Name | Affiliation | Role |
|---|---|---|
| Raja K Sivamani, MD MS AP | Study Principal Investigator | Principal Investigator |
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| ID | Term |
|---|---|
| D000152 | Acne Vulgaris |
| ID | Term |
|---|---|
| D017486 | Acneiform Eruptions |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D012625 | Sebaceous Gland Diseases |
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| Cotton Pillowcase |
| Other |
100% Cotton Pillowcase |
|
| 8 weeks |
| Skin Microbiome, relative abundance of C. acnes | Changes in skin microbiome relative abundance of C. acnes will be assessed with swab based collections of the facial skin microbiome | 8 Weeks |
| Skin Hydration | Skin Hydration measured with MoistureMeter | 8 Weeks |