Intradialytic aerobic exercise is not effective in increasing hemodialysis adequacy but is effective in improving physical performance in twice-weekly hemodialysis patients.

Uremic myopathy occurs in 60-75% of Chronic Kidney Disease (CKD) patients undergoing hemodialysis, which causes a decrease in muscle strength and physical performance. Increasing dialysis adequacy is beneficial in reducing the impact of uremia on muscles. Intradialytic aerobic exercise in thrice-weekly hemodialysis patients has improved dialysis adequacy and physical performance. This study aims to determine the effect of intradialytic aerobic exercise on improving dialysis adequacy and physical performance in twice-weekly hemodialysis patients.

Inclusion Criteria:

• End Stage Renal Disease Patient stage 5 with Glomerular Filtration Rate <15mL/minute/1.73m2 aged 25-54 years undergoing hemodialysis two times per week for three months to five years
• Hemoglobin levels > 8mg/dl
• Mini-Mental State Examination (MMSE) score of ≥24
• Hamilton Depression Rating Scale (HDRS) score <25

Exclusion Criteria:

• Received aerobic exercise in the last 3 months
• History of hospitalization in the last 3 months
• Access for hemodialysis circulation via the femoral vein.
• IMT <18,5 (underweight) dan ≥35 (obese class II)
• Non-stable cardiovascular disease, uncontrolled glucose, acute infection disease

The sample in this study was determined randomly using a computer; subjects in the treatment group underwent routine hemodialysis by committing to an intradialysis aerobic exercise program