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To evaluate the efficacy of drainage achieved by thoracoscopy vs tube drainage alone.
To compare clinical outcomes such as length of hospital stay, need for additional procedures, and treatment failure rates between the two drainage methods.
To asses resolution of pleural infection and rates of fluid re-accumulation over follow-up.
To compare safety profiles and complication rates of thoracoscopy versus tube drainage alone
Empyema is a serious infection characterized by pus accumulation in the pleural space. Effective drainage and treatment is necessary for resolution. Traditionally, intercostal tube placement was standard initial management. However, recent studies have compared outcomes of early medical thoracoscopy or video-assisted thoracoscopic surgery (VATS).
Thoracoscopy enables direct visualization for thorough pleural space cleansing and debridement under direct vision. medical thoracoscopy significantly improved drainage adequacy and reduced treatment failure risks compared to tube drainage alone. Also reported shorter hospital stays and lower complication rates with early thoracoscopy-directed management.
Additional benefits of thoracoscopy include enabling talc pleurodesis for reducing empyema recurrence. thoracoscopy-directed pleurodesis achieved higher long-term success rates than tube drainage followed by pleurodesis. Overall, current evidence indicates medical thoracoscopy provides superior empyema treatment outcomes to conventional tube drainage through optimized drainage and debridement under direct visualization.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Medical thoracoscopy group | Active Comparator | Medical thoracoscopy is a minimally invasive endoscopic procedure utilized by pulmonologists to evaluate, diagnose, and treat pleural pathologies of the lung, mainly pleural effusions. |
|
| Intercostal tube group | Active Comparator | Intercostal chest tube placed without thoracoscopy for patients with confirmed empyema. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Thoracoscopy procedure | Procedure | is a minimally invasive endoscopic procedure utilized by pulmonologists to evaluate, diagnose, and treat pleural pathologies of the lung, mainly pleural effusions. |
| Measure | Description | Time Frame |
|---|---|---|
| Treatment success: | Asses by chest ultrasound | baseline |
| Measure | Description | Time Frame |
|---|---|---|
| Success of pleurodesis | measured by assessing the recurrence rate of pleural effusion over a specified follow-up period. | baseline |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Hend saleh, MD | Contact | 01098988712 | hend.m.saleh@gmail.com | |
| Mohamed yassen, MD | Contact | 0100680052 | Mfawzy2013@hotmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Mustafa Ahmed, MD | Doctor | Study Chair |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31525811 | Background | Godfrey MS, Bramley KT, Detterbeck F. Medical and Surgical Management of Empyema. Semin Respir Crit Care Med. 2019 Jun;40(3):361-374. doi: 10.1055/s-0039-1694699. Epub 2019 Sep 16. | |
| 30955515 | Background | Aboudara M, Maldonado F. Update in the Management of Pleural Effusions. Med Clin North Am. 2019 May;103(3):475-485. doi: 10.1016/j.mcna.2018.12.007. |
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| ID | Term |
|---|---|
| D004653 | Empyema |
| ID | Term |
|---|---|
| D013492 | Suppuration |
| D007239 | Infections |
| D007249 | Inflammation |
| D010335 | Pathologic Processes |
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Medical thoracoscopy group
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Intercostal chest tube group
| Chest tube thoracostomy | Procedure | Insert chest intercostal tube without thoracoscopy |
|
| D013568 |
| Pathological Conditions, Signs and Symptoms |