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| ID | Type | Description | Link |
|---|---|---|---|
| 2023-01566 | Other Identifier | EKNZ |
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The goal of this clinical trial is to analyse the prevalence of new or uncontrolled arterial hypertension (AHT) after hospital discharge of medical in-patients with elevated blood pressure (BP) values during hospitalisation.
The main questions it aims to answer are:
Participants will either be treated according to their physicians' decision or antihypertensive treatment adaptions will be postponed until after hospital discharge.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Usual practice arm | No Intervention | Patients will be treated according to their treating physicians' decision. | |
| Postponement of treatment arm | Other | Antihypertensive treatment adaptions will be postponed until after a 24h ambulatory blood pressure measurement (ABPM) 4 weeks after hospital discharge. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Postponement of antihypertensive treatment | Other | Hypertensive blood pressure values in medical in-patients will not be treated during hospitalisation until confirmed by ABPM 4 weeks after hospital discharge |
| Measure | Description | Time Frame |
|---|---|---|
| Prevalence of persisting new or uncontrolled arterial hypertension | Elevated blood pressure values in ambulatory blood pressure monitoring | 4 weeks after hospital discharge |
| Prevalence of a combined hypertensive complication endpoint | Consisting of intracerebral bleeding, ischemic stroke, myocardial infarction, cardiovascular death or cardiovascular re-hospitalization | Until 4 weeks after hospital discharge |
| Prevalence of a combined hypotensive complication endpoint | Consisting of falls, acute kidney injury, electrolyte disturbances, re-hospitalizations due to hypotension, or BP values on ABPM below the lower treatment limit | Until 4 weeks after hospital discharge |
| Measure | Description | Time Frame |
|---|---|---|
| Clinic blood pressure measurement in mmHg | Documented in the patient documentation | At baseline |
| Research blood pressure measurement in mmHg | Standardized blood pressure measurement taken by research staff |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Annina Vischer, M.D. | Contact | +41612652525 | annina.vischer@usb.ch |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Hospital Basel | Recruiting | Basel | 4031 | Switzerland |
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| ID | Term |
|---|---|
| D006973 | Hypertension |
| ID | Term |
|---|---|
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
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There will be block-wise randomization. During the first block, the study team will not interfere with the treating physician, in order to ensure that they will treat the patient according to what they perceive as the current usual practice. During the second block the patients receive no change of their original antihypertensive treatment.
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In the first block, the treating physicians will not be informed about the study participation of their patient, in order to ensure that they will treat the patient according to what they perceive as the current usual practice. In the second block, the treating physicians will be informed about the study participation of their patients.
| At baseline |
| Prevalence of previously unknown arterial hypertension | No previously documented diagnosis of arterial hypertension and no antihypertensive treatment | At baseline |
| Prevalence of female gender | As reported by participant | At baseline |
| Prevalence of re-hospitalization for any cause | According to hospital documentation and patient interrogation | Until 4 weeks after hospital discharge |