The Relationship Between NLR and PONV and ESPB

The Relationship Between the Preoperative Neutrophil-to-lymphocyte Ratio (NLR) and Postoperative Nausea and Vomiting (PONV) in Lumbar Spine Surgery Patients, as Well as the Impact of Erector Spinae Plane Block on NLR and PONV

This study aims to investigate whether preoperative NLR (Neutrophil-to-Lymphocyte Ratio) serves as a biomarker for PONV (Postoperative Nausea and Vomiting). It also examines the impact of erector spinae plane block on NLR and PONV. Furthermore, the research explores the effect of erector spinae plane block on postoperative pain relief in spinal surgery and its influence on the usage of opioid medications.

Inclusion Criteria:

1. Patients undergoing elective posterior lumbar spine surgery in a prone position under general anesthesia.
2. ASA classification grades I to II.
3. Age between 18 and 80 years old.
4. Signed the informed consent for this study.

Exclusion Criteria:

1. Preoperative blood transfusion.
2. Uncontrolled systemic diseases.
3. Patients with known uncontrolled systemic inflammatory diseases (e.g., rheumatoid arthritis, lupus, or active infections).
4. Gastrointestinal system disorders.
5. History of antiemetic and anticholinergic drug use.
6. History of adverse reactions related to surgery, deformity correction surgeries, defined as procedures involving instrumentation across three or more levels or aimed at correcting scoliosis or kyphosis.
7. Severe spinal deformities.
8. Infection at the puncture site.
9. Coagulation disorders.
10. Long-term use of sedatives and analgesic drugs before surgery.
11. Patients with mental illness or communication barriers.
12. Allergic to ropivacaine.
13. Participants involved in other clinical studies within the past 3 months.
14. History of previous lumbar surgeries.
15. Subjective unwillingness to participate in this study.