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The aim of this study is to evaluate the flexible ureteroscope (FURS) technique with and without ureteral access sheath (UAS).
Treating a large renal stone, more than 2 cm, is changing during the last decades. Technological innovations have led to a significant improvement in flexible ureteroscopes over recent years.
Many authors have used flexible ureteroscope (FURS) with laser fragmentation as proved treating modality with high efficacy. Although percutaneous extraction of large renal stones is still the first option, it has higher and more severer complications than flexible ureteroscopy.
FURS has developed into a standard diagnostic and treatment modality for upper urinary stone disease, transitional cell carcinoma and ureteral strictures. Indeed, more recently FURS is becoming a minimally invasive competitor to percutaneous nephrolithotomy for larger kidney stones as well as an accepted modality for localized treatment of small upper urinary tract transitional cell carcinoma.
The use of ureteral access sheath (UAS) is widely recognized as a technique utilized to keep the intrarenal pressure low when performing FURS for larger and more complex stones, although some authors advocate its use for most renal stones. UASs are now produced with varying characteristics including various lengths, diameters, materials, dilator tip designs, radiopaque markers, and stiffness. However, it also rises surgical costs and may injure the ureteral wall.
Most common reasons cited by urologists for using a UAS are to facilitate repeated entrance into the ureter and collecting system (as a time-saver), lower intrarenal pressure and protection of ureteroscope and ureter when extracting stone fragments. UAS has encouraged urologists in the fragmentation of large stones; it facilitates multiple entries and stone extraction during FURS.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Flexible ureteroscope with ureteral access sheath | Experimental | Stones will be treated by flexible ureteroscope with ureteral access sheath |
|
| Flexible ureteroscope without ureteral access sheath | Active Comparator | Stones will be treated by flexible ureteroscope without ureteral access sheath |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Flexible ureteroscope with ureteral access sheath | Procedure | The flexible ureteroscope either directly or via an access sheath, depending on the size of the ureter, a 9.5/11.5 Fr or a 12 Fr access sheath will be used. |
| Measure | Description | Time Frame |
|---|---|---|
| Operative time | Time from sterilization till the end of surgery | Intraperatively |
| Measure | Description | Time Frame |
|---|---|---|
| Stone-free rate | Stone-free status was defined as no residual stones or residual stones with a maximum diameter ≤ 4 mm with no clinical symptoms at 1 month after the procedure | 28 days after intervention |
| Complications |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| New Valley University | New Valley | New Valley Governorate | 72511 | Egypt |
The data will be available upon a reasonable request from the corresponding author after the end of study for one year.
After the end of study for one year.
The data will be available upon a reasonable request from the corresponding author.
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| Flexible ureteroscope without ureteral access sheath | Procedure | Ureteroscopy will be carried out without a ureteral access sheath |
|
Complications such as mucosal lacerations, bleeding, urosepsis, and stein Strasse.
| 28 days after intervention |
| Duration of stay | Time from admission till hospital discharge | 28 days after intervention |
| Number of patients who need ancillary procedures | Need for Ancillary Procedures if there was residual. | 28 days after intervention |