Exploring the Benefit of Neuromodulation in Treating Chemo-induced Peripheral Neuropathy Using Peripheral Neuropathy Markers (Meissner's Corpuscles and Epidermal Nerve Fiber Density) and Sensory Testing (Quantitative Sensory and Gait Testing): A Single Center Feasibility Study

Exploring the Benefit of Neuromodulation in Treating Chemo-induced Peripheral Neuropathy Using Peripheral Neuropathy Markers (Meissner's Corpuscles and Epidermal Nerve Fiber Density) and Sensory Testing (Quantitative Sensory and Gait Testing): A Single Center Feasibility Study

To learn if a process called neuromodulation can help to improve pain due to CIP

Inclusion Criteria:

• Ability to understand and the willingness to sign a written informed consent document
• Patients diagnosed with CIPN lower extremity due to either vinca alkaloids, taxanes, bortezomib, thalidomide, platinum-based compounds
• Patients seen at Pain Management Center at MD Anderson Cancer Center
• Patient ages greater or equal to 18 years but less than or equal to 85 years

Exclusion Criteria:

• Patients with cognitive dysfunction
• Patient with recent history (<6 months) of drug or alcohol abuse
• Patients with open skin lesion or undergoing antibiotic therapy for local for systemic infection
• Patients with painful diabetic peripheral neuropathy or preexisting peripheral neuropathy

Inclusion Criteria:

• Ability to understand and the willingness to sign a written informed consent document
• Patients diagnosed with CIPN lower extremity due to either vinca alkaloids, taxanes, bortezomib, thalidomide, platinum-based compounds
• Patients seen at Pain Management Center at MD Anderson Cancer Center
• Patient ages greater or equal to 18 years but less than or equal to 85 years

Exclusion Criteria

• Patients with cognitive dysfunction
• Patient with recent history (<6 months) of drug or alcohol abuse
• Patients with open skin lesion or undergoing antibiotic therapy for local for systemic infection
• Patients with painful diabetic peripheral neuropathy or preexisting peripheral neuropathy