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| Name | Class |
|---|---|
| East Tennessee State University | OTHER |
| University of North Carolina, Chapel Hill | OTHER |
| Ballad Health | OTHER |
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Consumption of unsafe drinking water is associated with a substantial burden of disease globally. In the USA, the burden of disease associated with consumption of contaminated drinking water from non-regulated private wells and springs in rural areas is relatively understudied and unclear. For some lower-income households in rural areas of the USA without access to reliably safe drinking water, point-of-use treatment with relatively low-cost pitcher filters could help to reduce exposures to contaminated water and associated adverse health outcomes. This pilot randomized controlled intervention trial will provide information and data on water quality and contamination exposures, associated health outcomes, and the adoption potential of point-of-use water filters in rural areas of Virginia and Tennessee.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Treatment | Active Comparator | Households randomized to the treatment group will be provided countertop pitcher water filters |
|
| Control | No Intervention | Households randomized to the control group will be provided water filters at the completion of the study |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Countertop pitcher water filter | Device | Point-of-use drinking water filter |
|
| Measure | Description | Time Frame |
|---|---|---|
| E. coli detection in drinking water | Proportion of households with E. coli (indicator of fecal contamination) detected in drinking water samples | 12 months |
| Heavy metals or other contaminants exceeding EPA MCL | Proportion of households with contaminants detected in drinking water at concentrations exceeding the US Environmental Protection Agency (EPA) Safe Drinking Water Act (SDWA) Maximum Contaminant Levels (MCL) | 12 months |
| Measure | Description | Time Frame |
|---|---|---|
| Gastrointestinal illness | Incidence of acute gastrointestinal illness via self-reported diarrhea (7-day recall) | 12 months |
| Pathogen infection | Detection of enteric pathogen infection via qPCR analysis of stool samples and salivary antibody assays |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Alasdair Cohen, PhD | Virginia Polytechnic Institute and State University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| East Tennessee State University | Johnson City | Tennessee | 37614 | United States | ||
| Virginia Tech |
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| ID | Term |
|---|---|
| D000069578 | Waterborne Diseases |
| ID | Term |
|---|---|
| D007239 | Infections |
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| 12 months |
| Blacksburg |
| Virginia |
| 24061 |
| United States |