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| Name | Class |
|---|---|
| Sheba Medical Center | OTHER_GOV |
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Piano playing may provide an engaging and accessible setting for finger and wrist movement training. Moreover, it has been found effective for improving manual dexterity and upper-limb function in other neurologic disorders, such as stroke and additionally beneficial for cognitive and psychosocial support in Parkinson's disease. However, no study has examined the effect of piano playing on dexterity in Parkinson's disease. The aim of this study is to test the efficacy of a novel piano-based training program on fine motor function in patients with PD. Participants with Parkinson's disease will take part in an individually tailored 6-week piano training program, combining weekly supervised training sessions (6x60 min altogether), with three independent at-home weekly 30 minutes practice sessions (18x30 altogether). Participants will receive a piano MIDI keyboard for home use during the study.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Research group | Experimental | Receives the full piano training |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Piano | Behavioral | Receives the piano training |
|
| Measure | Description | Time Frame |
|---|---|---|
| Box and block test | Number of blocks that can be moved over a barrier using the hand / arm in one minute | First meeting, last meeting (after 6 weeks) |
| 9 Hole peg test | Time taken to insert 9 pegs into holes and then remove them | First meeting, last meeting (after 6 weeks) |
| Synergy index | Calculated from a force ramp production task using the fingers with force sensors | First meeting, last meeting (after 6 weeks) |
| Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) motor parts II (patient questionnaire) - parts 2.4 to 2.7 and III (motor examination) - parts 3.3 and 3.4 | Standard questionnaire used in Parkinson's disease. Higher scores indicate more impairment. Maximum score for each part is 4, so overall for the 6 parts the maximum score is 24. | First meeting, last meeting (after 6 weeks) |
| Measure | Description | Time Frame |
|---|---|---|
| Quantitative Digitography - Average strike duration | Measure of speed and variability of key presses on a piano - mean of the time the key is pressed | First meeting, last meeting (after 6 weeks) |
| Quantitative Digitography - Coefficient of variation strike duration |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Tel Aviv University | Tel Aviv | 6997801 | Israel |
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| ID | Type | URL | Comment |
|---|---|---|---|
| 10.6084/m9.figshare.23994768 | Informed Consent Form | View IPD |
Anonymous raw data from the tests will be made available on figshare
Upon publication
Open to all
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| ID | Term |
|---|---|
| D010300 | Parkinson Disease |
| ID | Term |
|---|---|
| D020734 | Parkinsonian Disorders |
| D001480 | Basal Ganglia Diseases |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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Open label feasibility study
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Measure of speed and variability of key presses on a piano - coefficient of variation of the time the key is pressed |
| First meeting, last meeting (after 6 weeks) |
| Quantitative Digitography - Average interval between strikes (in seconds) | Measure of speed and variability of key presses on a piano - average time between subsequent key presses | First meeting, last meeting (after 6 weeks) |
| Quantitative Digitography - Coefficient of variation of interval between strikes | Measure of speed and variability of key presses on a piano - coefficient of variation of the time between subsequent key presses | First meeting, last meeting (after 6 weeks) |
| Quantitative assessment of piano performance progress | Measurement of improvement in playing the piano - the teacher (rater) will give a score (between 0 and 5) for the level of piano playing of the participant, where 0 is no ability to play and 5 is the ability to play the pieces from the workbook (a beginner's level piano book) perfectly. | First meeting, last meeting (after 6 weeks) |
| 10.6084/m9.figshare.23994768 | Individual Participant Data Set | View IPD |
| D009422 | Nervous System Diseases |
| D009069 | Movement Disorders |
| D000080874 | Synucleinopathies |
| D019636 | Neurodegenerative Diseases |